Amino acids are natural compounds that can be safely used in pharmaceutical applications.
Considering the great interest in the amino acids used in the pharmaceutical industry, this …

The occurrence of tautomeric polymorphism in the Cambridge Structural Database (CSD)
was established to be very rare in a previous study by AJ Cruz-Cabeza and CR Groom …

Drug repositioning refers to the identification of new therapeutic indications for drugs already
approved. Albendazole and ricobendazole have been used as anti-parasitic drugs for many …

Albendazole is an effective antihelmintic drug, which has an unpredictable therapeutic
response due to its low solubility in biological fluids that limits its oral absorption. In an …

The aim of this study was to use a combined in vitro-in silico approach to develop a
physiologically based pharmacokinetic model (PBPK) that predicts the bioavailability of …

Albendazole, an anthelmintic recognized by the World Health Organization as an essential
medicine, is known to have limitations in solubility and bioavailability. To improve these …

Introduction N-phenyl-2-(aniline) analog N53 is a previously discovered dual inhibitor of
Topo I and COX-2, which exhibited significant anti-colon cancer activity in vitro, but the poor …

Simple Summary Anthelmintic drugs are among those most widely used in veterinary
practice. The development of resistance to these drugs is a widespread problem, especially …

The structural, spectroscopic (FT-IR and FT-Raman), and physicochemical properties of
ricobendazole (RBZ) has been presented with the help of combined experimental and …

The present investigation deals with enhancement of dissolution rate of high dose drug
albendazole (ABZ) using liquisolid compacts. Study of precompression characteristics …