Molecular diagnosis of tuberculosis

F Nurwidya, D Handayani, E Burhan… - Chonnam medical …, 2018 - synapse.koreamed.org
Tuberculosis (TB) is one of the leading causes of adult death in the Asia-Pacific Region,
including Indonesia. As an infectious disease caused by Mycobacterium tuberculosis (MTB) …

An inflammatory story: antibodies in tuberculosis comorbidities

MR McLean, LL Lu, SJ Kent, AW Chung - Frontiers in immunology, 2019 - frontiersin.org
Mycobacterium tuberculosis (Mtb) resides in a quarter of the world's population and is the
causative agent for tuberculosis (TB), the most common infectious reason of death in …

Evaluation of matricellular proteins in systemic and local immune response to Mycobacterium tuberculosis infection

FM Hasibuan, B Shiratori, MA Senoputra… - Microbiology and …, 2015 - Wiley Online Library
Matricellular proteins such as osteopontin (OPN), galectin‐9 (Gal‐9), and tenascin‐C (TN‐
C) are expressed not only under normal physiological conditions, but also during infection …

[HTML][HTML] Differences in IgG responses against infection phase related Mycobacterium tuberculosis (Mtb) specific antigens in individuals exposed or not to Mtb correlate …

M Coppola, L Arroyo, KE van Meijgaarden… - Tuberculosis, 2017 - Elsevier
Tuberculosis (TB) occurs in only 3–10% of Mycobacterium tuberculosis (Mtb) infected
individuals, suggesting that natural immunity can contain Mtb infection, although this …

Immune responses to Mycobacterium tuberculosis membrane-associated antigens including alpha crystallin can potentially discriminate between latent infection and …

SK Kumar, S Arya, A Aggarwal, P Kapoor, A Nath… - PLoS …, 2020 - journals.plos.org
Changes in expression of membrane antigens may accompany the transition of
Mycobacterium tuberculosis (Mtb) from 'dormant'to 'active'states. We have determined …

Development of point-of-care testing for disaster-related infectious diseases

T Hattori, H Chagan-Yasutan, B Shiratori… - The Tohoku Journal of …, 2016 - jstage.jst.go.jp
After disaster, the victims lose their safe lives and are even exposed to nature where they
could suffer from animal bites and vectors followed by suffering from zoonosis or vector-born …

Use of DosR Dormancy Antigens from Mycobacterium tuberculosis for Serodiagnosis of Active and Latent Tuberculosis

SD Shi, PR Hsueh, PC Yang, CC Chou - ACS Infectious Diseases, 2019 - ACS Publications
As more than two billion people possibly have a latent tuberculosis (LTB) infection, early
LTB diagnosis is crucial for the efficient control and elimination of tuberculosis (TB). The aim …

Single Nucleotide Polymorphisms in P2X7 Gene Are Associated with Serum Immunoglobulin G Responses to Mycobacterium tuberculosis in Tuberculosis Patients

J Wu, L Lu, L Zhang, Y Ding, F Wu, W Zuo… - Disease …, 2015 - Wiley Online Library
Objective. Our study investigated the association between single nucleotide polymorphisms
(SNPs) in P2X7 gene and serum immunoglobulin G (IgG) responses to mycobacterium …

Immunoscreening of the M. tuberculosis F15/LAM4/KZN secretome library against TB patients′ sera identifies unique active-and latent-TB specific biomarkers

TE Chiliza, M Pillay, K Naidoo, B Pillay - Tuberculosis, 2019 - Elsevier
Tuberculosis (TB) protein biomarkers are urgently needed for the development of point-of-
care diagnostics, new drugs and vaccines. Mycobacterium tuberculosis extracellular and …

Combining urine lipoarabinomannan with antibody detection as a simple non-sputum-based screening method for HIV-associated tuberculosis

H Younis, I Kerschbaumer, JY Moon, RS Kim… - PLoS …, 2019 - journals.plos.org
Background Simple methods for the accurate triaging and screening of HIV-associated
tuberculosis (TB) are urgently needed. We hypothesized that combining serum antibody with …