A review of recent synthetic strategies and biological activities of isoxazole

CP Pandhurnekar, HC Pandhurnekar… - Journal of …, 2023 - Wiley Online Library
Among different heterocyclic compounds, isoxazole and their analogues are very important
classes of heterocyclic compounds as they display an extensive range of biological actions …

Research progress on the synthesis and pharmacology of 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole derivatives: a mini review

JJ Wang, W Sun, WD Jia, M Bian… - Journal of Enzyme …, 2022 - Taylor & Francis
Oxadiazole is a five-membered heterocyclic compound containing two nitrogen atoms and
one oxygen atom. The 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole have favourable physical …

Antivirals blocking entry of enteroviruses and therapeutic potential

MI Anasir, F Zarif, CL Poh - Journal of Biomedical Science, 2021 - Springer
Viruses from the genus Enterovirus (EV) of the Picornaviridae family are known to cause
diseases such as hand foot and mouth disease (HFMD), respiratory diseases, encephalitis …

Combating coxsackievirus B infections

A Alhazmi, MP Nekoua, A Mercier… - Reviews in Medical …, 2023 - Wiley Online Library
Coxsackieviruses B (CVB) are small, non‐enveloped, single‐stranded RNA viruses
belonging to the Enterovirus genus of the Picornaviridae family. They are common …

Visible light mediated eosin-Y catalysed synthesis of benzylidene-methylisoxazolone

R Kumar, K Garima, V Srivastava, PP Singh… - Tetrahedron Letters, 2023 - Elsevier
An eco-friendly green and metal-free visible light mediated approach for the synthesis of
biologically potent 4-benzylidene-3-methylisoxazol-5 (4H)-one through multifactorial …

Design, synthesis, In-vitro, In-silico and DFT studies of novel functionalized isoxazoles as antibacterial and antioxidant agents

A Arzine, O Abchir, M Chalkha, K Chebbac… - … Biology and Chemistry, 2024 - Elsevier
A series of new isoxazolederivatives incorporating the sulfonate ester function has been
synthesized from 2-benzylidenebenzofuran-3 (2 H)-one, known as aurone. The synthesis of …

Synthesis, characterization, DFT, docking studies and molecular dynamics of some 3-phenyl-5-furan isoxazole derivatives as anti-inflammatory and anti-ulcer agents

HM Pallavi, FH Al-Ostoot, HK Vivek… - Journal of Molecular …, 2022 - Elsevier
A vast number of nitrogen heterocyclic derivatives comprising oxygen atom is considered as
a valuable combination of therapeutic agents in curative chemistry. In particular, isoxazole, a …

The in vitro impact of Isoxazole derivatives on pathogenic biofilm and cytotoxicity of fibroblast cell line

U Bąchor, A Junka, M Brożyna… - International Journal of …, 2023 - mdpi.com
The microbial, biofilm-based infections of chronic wounds are one of the major challenges of
contemporary medicine. The use of topically administered antiseptic agents is essential to …

Investigation of the molecular mechanism and diastereoselectivity in the [3+ 2] cycloaddition reaction between acetonitrile oxide and Cis-3, 4-Dichlorocyclobutene …

AO Aitouna, H Mohammad-Salim, A Zeroual… - Computational and …, 2023 - Elsevier
cycloaddition (32CA) reactions involving acetonitrile oxide 1 and cis-3, 4-
dichlorocyclobutene 2 has been investigated via Molecular Electron Density Theory (MEDT) …

6-methylguanamine-Supported CoFe2O4: An Efficient Catalyst for One-Pot Three-Component Synthesis of Isoxazol-5(4H)-One Derivatives

HR Saadati-Moshtaghin, B Maleki… - Polycyclic Aromatic …, 2022 - Taylor & Francis
In this study, an efficient and magnetically recoverable catalyst consisting of 6-
methylguanamine supported on CoFe2O4 nanoparticles for the preparation of isoxazol-5 (4 …