Deinococcus radiodurans is a robust bacterium best known for its capacity to repair massive
DNA damage efficiently and accurately. It is extremely resistant to many DNA-damaging …

A large and complex gene on the X chromosome encodes dystrophin. Many mutations have
been described in this gene, most of which affect the expression of the muscle isoform, the …

Long interspersed nuclear elements (LINE-1 or L1) comprise 17% of the human genome,
although only 80–100 L1s are considered retrotransposition-competent (RC-L1). Despite …

The fucosyltransferase gene family encodes enzymes that transfer fucose in α1, 2, α1, 3/4
and α1, 6 linkages on a large variety of glycans. The most ancient genes harbour a split …

Psoriasis is a chronic inflammatory skin disease characterized by excessive proliferation of
keratinocytes (KCs). Onset of psoriasis is related to genetic, immune and environmental …

MECP2 mutations are responsible for Rett syndrome (RTT). Approximately a quarter of
classic RTT cases, however, do not have an identifiable mutation of the MECP2 gene. We …

Telomeres, the ends of linear chromosomes, play a major role in the maintenance of
genome integrity. Telomerase or alternative lengthening of telomeres (ALT) mechanisms …

Abstract Allelic deletions of 10q25–26 and 19q13. 3–13.4 are the most common genetic
alterations in glial tumors. We have identified a balanced t (10; 19) reciprocal translocation …

APOBEC3G (apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G) is an
innate intracellular antiretroviral factor that can inhibit viral retroelements such as …

Polymorphism for deletions was investigated in 1027 lines of tetraploid and hexaploid wheat
and 420 lines of wheat diploid ancestors. A total of 26 deletions originating during the …