Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

M Fenech, M Kirsch-Volders, AT Natarajan… - …, 2011 - academic.oup.com
Micronuclei (MN) and other nuclear anomalies such as nucleoplasmic bridges (NPBs) and
nuclear buds (NBUDs) are biomarkers of genotoxic events and chromosomal instability …

Atypical choroid plexus papilloma: clinical experience in the CPT-SIOP-2000 study

B Wrede, M Hasselblatt, O Peters, PF Thall… - Journal of neuro …, 2009 - Springer
Atypical choroid plexus papilloma (APP) represents a novel intermediate-grade subtype of
choroid plexus tumor (CPT), the clinical outcome of which has not been described yet. We …

miR-181b modulates glioma cell sensitivity to temozolomide by targeting MEK1

J Wang, K Sai, F Chen, Z Chen - Cancer chemotherapy and …, 2013 - Springer
Purpose Recent studies have reported that miR-181b contributes to chemoresistance in
several cancer types and functions as a tumor suppressor in glioma. This study aimed to …

MiR-181b sensitizes glioma cells to teniposide by targeting MDM2

Y Sun, J Wang, C Guo, K Sai, J Wang, F Chen, Q Yang… - BMC cancer, 2014 - Springer
Background Although the incidence of glioma is relatively low, it is the most malignant tumor
of the central nervous system. The prognosis of high-grade glioma patient is very poor due …

Choroid plexus carcinomas are characterized by complex chromosomal alterations related to patient age and prognosis

V Ruland, S Hartung, U Kordes, JE Wolff… - Genes …, 2014 - Wiley Online Library
Choroid plexus carcinoma is a malignant brain tumor predominantly occurring in young
children. Only limited data are available regarding the underlying molecular genetic …

Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells

KS Borges, AM Castro-Gamero, DA Moreno… - Journal of cancer …, 2012 - Springer
Background Glioblastoma remains one of the most devastating human malignancies, and
despite therapeutic advances, there are no drugs that significantly improve the patient …

Cytogenetic findings in pediatric radiation-induced atypical meningioma after treatment of medulloblastoma: case report and review of the literature

MS Brassesco, ET Valera, L Neder, JA Pezuk… - Journal of neuro …, 2012 - Springer
Ionizing radiation is the most recognized risk factor for meningioma in pediatric long-term
cancer survivors. Information in this rare setting is exceptional. We report the clinical and …

Tetra-O-methyl nordihydroguaiaretic acid, an inhibitor of Sp1-mediated survivin transcription, induces apoptosis and acts synergistically with chemo-radiotherapy in …

AM Castro-Gamero, KS Borges, DA Moreno… - Investigational new …, 2013 - Springer
Glioblastoma (GBM), one of the most malignant human neoplasias, responds poorly to
current treatment modalities, with temozolomide (TMZ) being the drug most frequently used …

Low-grade astrocytoma in a child with encephalocraniocutaneous lipomatosis

MS Brassesco, ET Valera, AP Becker… - Journal of neuro …, 2010 - Springer
Encephalocutaneous lipomatosis (ECCL), or Haberland syndrome, is an uncommon
congenital disorder with unique cutaneous, ocular and neurological features. In the present …

Mucoepidermoid carcinoma of the lung arising at the primary site of a bronchogenic cyst: clinical, cytogenetic, and molecular findings

MS Brassesco, ET Valera, RCP Lira… - Pediatric Blood & …, 2011 - Wiley Online Library
Primary lung tumors are rare in children, and mucoepidermoid carcinoma (MEC) represents
less than 10% of them. Additionally, MEC arising from bronchogenic cysts (BC) is …