Identification of bioactive metabolites using activity metabolomics

MM Rinschen, J Ivanisevic, M Giera… - Nature reviews Molecular …, 2019 - nature.com
The metabolome, the collection of small-molecule chemical entities involved in metabolism,
has traditionally been studied with the aim of identifying biomarkers in the diagnosis and …

Lipidomics from sample preparation to data analysis: a primer

T Züllig, M Trötzmüller, HC Köfeler - Analytical and bioanalytical chemistry, 2020 - Springer
Lipids are amongst the most important organic compounds in living organisms, where they
serve as building blocks for cellular membranes as well as energy storage and signaling …

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

Y Perez-Riverol, J Bai, C Bandla… - Nucleic acids …, 2022 - academic.oup.com
Abstract The PRoteomics IDEntifications (PRIDE) database (https://www. ebi. ac. uk/pride/) is
the world's largest data repository of mass spectrometry-based proteomics data. PRIDE is …

The PRIDE database and related tools and resources in 2019: improving support for quantification data

Y Perez-Riverol, A Csordas, J Bai… - Nucleic acids …, 2019 - academic.oup.com
Abstract The PRoteomics IDEntifications (PRIDE) database (https://www. ebi. ac. uk/pride/) is
the world's largest data repository of mass spectrometry-based proteomics data, and is one …

To metabolomics and beyond: a technological portfolio to investigate cancer metabolism

F Danzi, R Pacchiana, A Mafficini, MT Scupoli… - … and Targeted Therapy, 2023 - nature.com
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …

Foodomics: Analytical opportunities and challenges

A Valdés, G Alvarez-Rivera… - Analytical …, 2021 - ACS Publications
Food analysis has traditionally been an important field of application of analytical chemistry.
Indeed, administrations, governments, consumers, and researchers worldwide rely on …

High resolution mass spectrometry in lipidomics

T Züllig, HC Köfeler - Mass spectrometry reviews, 2021 - Wiley Online Library
The boost of research output in lipidomics during the last decade is tightly linked to improved
instrumentation in mass spectrometry. Associated with this trend is the shift from low …

Metabolomics: small molecules that matter more

BC Muthubharathi, T Gowripriya, K Balamurugan - Molecular omics, 2021 - pubs.rsc.org
Metabolomics, an analytical study with high-throughput profiling, helps to understand
interactions within a biological system. Small molecules, called metabolites or metabolomes …

ThermoRawFileParser: modular, scalable, and cross-platform RAW file conversion

N Hulstaert, J Shofstahl, T Sachsenberg… - Journal of proteome …, 2019 - ACS Publications
The field of computational proteomics is approaching the big data age, driven both by a
continuous growth in the number of samples analyzed per experiment as well as by the …

[HTML][HTML] Metabolite discovery: Biochemistry's scientific driver

M Giera, O Yanes, G Siuzdak - Cell metabolism, 2022 - cell.com
Metabolite identification represents a major challenge, and opportunity, for biochemistry.
The collective characterization and quantification of metabolites in living organisms, with its …