The subject of crystal engineering started in the 1970s with the study of topochemical
reactions in the solid state. A broad chemical definition of crystal engineering was published …

The search for a suitable replacement for the ubiquitous oxidizer ammonium perchlorate
(AP) is a top priority to enable more sustainable solid rocket motors. The oxidizing salts …

Acefylline (ACF) is a stimulant xanthine derivative drug, which is formulated as a piperazine
salt for the treatment of bronchial asthma. ACF falls under BCS class IV category of low …

Control over thermal expansion (TE) behaviors in solid materials is often accomplished by
modifying the molecules or intermolecular interactions within the solid. Here, we use a …

The discovery of new crystalline forms of large, flexible drug molecules is of significant
interest to the pharmaceutical industry as a means of improving one or more …

In contrast to the mature predictive frameworks applied to neutral cocrystals, ionic cocrystals,
those including an ion pair, are difficult to design. Furthermore, they are generally excluded …

Levamisole hydrochloride cocrystallizes with hydroquinone in different solvates (methanol,
ethanol, water, acetonitrile, and n-propanol), forming the changing Z ″cocrystal solvates …

Tetramethylpyrazine (TMP) is used clinically to treat cardiovascular disease and ischemic
cerebrocardial vascular disease. However, the high sublimation tendency of TMP leads to its …

We present several multicomponent crystalline species formed by zwitterionic GABA
analogues pregabalin and phenibut. These compounds are evaluated based on their crystal …

Polycyclic aromatic hydrocarbons (PAHs) are a type of organic compounds consisting of at
least two or more fused aromatic rings. PAHs are frequently found in the environment and …