[PDF][PDF] Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications

BR Stockwell - Cell, 2022 - cell.com
Ferroptosis, a form of cell death driven by iron-dependent lipid peroxidation, was identified
as a distinct phenomenon and named a decade ago. Ferroptosis has been implicated in a …

Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy

B Niu, K Liao, Y Zhou, T Wen, G Quan, X Pan, C Wu - Biomaterials, 2021 - Elsevier
Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …

Ferulic acid: A review of its pharmacology, pharmacokinetics and derivatives

D Li, Y Rui, S Guo, F Luan, R Liu, N Zeng - Life sciences, 2021 - Elsevier
Ferulic acid, a kind of phenolic substance widely existing in plants, is an important active
component of many traditional Chinese medicines. So far, it has been proved that ferulic …

Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential

N Xie, L Zhang, W Gao, C Huang, PE Huber… - Signal transduction and …, 2020 - nature.com
Nicotinamide adenine dinucleotide (NAD+) and its metabolites function as critical regulators
to maintain physiologic processes, enabling the plastic cells to adapt to environmental …

Oxidative stress mitigation by antioxidants-an overview on their chemistry and influences on health status

AM Pisoschi, A Pop, F Iordache, L Stanca… - European Journal of …, 2021 - Elsevier
The present review paper focuses on the chemistry of oxidative stress mitigation by
antioxidants. Oxidative stress is understood as a lack of balance between the pro-oxidant …

Antioxidants and antioxidant methods: An updated overview

İ Gulcin - Archives of toxicology, 2020 - Springer
Antioxidants had a growing interest owing to their protective roles in food and
pharmaceutical products against oxidative deterioration and in the body and against …

Biomarkers of oxidative stress and antioxidant defense

S Demirci-Cekic, G Özkan, AN Avan, S Uzunboy… - … of pharmaceutical and …, 2022 - Elsevier
A number of reactive oxygen and nitrogen species are produced during normal metabolism
in human body. These species can be both radical and non-radical and have varying …

Antioxidants: Classification, natural sources, activity/capacity measurements, and usefulness for the synthesis of nanoparticles

J Flieger, W Flieger, J Baj, R Maciejewski - Materials, 2021 - mdpi.com
Natural extracts are the source of many antioxidant substances. They have proven useful not
only as supplements preventing diseases caused by oxidative stress and food additives …

Oxidative stress in oocyte aging and female reproduction

L Wang, J Tang, L Wang, F Tan, H Song… - Journal of cellular …, 2021 - Wiley Online Library
In a healthy body, reactive oxygen species (ROS) and antioxidants remain balanced. When
the balance is broken toward an overabundance of ROS, oxidative stress appears and may …