Although it was long thought that eukaryotic translation almost always initiates at an AUG
start codon, recent advancements in ribosome footprint mapping have revealed that non …

Apoptosis, a form of programmed cell death, is responsible for eliminating damaged or
unnecessary cells in multicellular organisms. Various types of intracellular stress trigger …

Abstract Cancer/testis (CT) antigens, of which more than 40 have now been identified, are
encoded by genes that are normally expressed only in the human germ line, but are also …

Cancer/testis (CT) antigens are immunogenic in cancer patients, exhibit highly tissue-
restricted expression, and are considered promising target molecules for cancer vaccines …

Autoantibodies against autologus tumor‐associated antigens have been detected in the
asymptomatic stage of cancer and can thus serve as biomarkers for early cancer diagnosis …

Background Pancreatic cancer is one of the most lethal type of cancers, with an overall five-
year survival rate of less than 5%. It is usually diagnosed at an advanced stage with limited …

For more than 15 years, TPX2 has been studied as a factor critical for mitosis and spindle
assembly. These functions of TPX2 are attributed to its Ran-regulated microtubule …

Lung cancer is the most common cause of neoplasia-related death worldwide. One of the
crucial early events in carcinogenesis is the induction of genomic instability and mutator …

Cancer/testis‐associated genes (CTAs) are a subgroup of tumor antigens with a restricted
expression in testis and malignancies. During the last decade, many of these …

The melanoma antigen (MAGE) proteins all contain a MAGE homology domain. MAGE
genes are conserved in all eukaryotes and have expanded from a single gene in lower …