Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations: a systematic review

S Galmiche, LBL Nguyen, E Tartour… - Clinical Microbiology …, 2022 - Elsevier
Background Available data show that COVID-19 vaccines may be less effective in
immunocompromised populations, who are at increased risk of severe COVID-19 …

Immunogenicity and risk factors associated with poor humoral immune response of SARS-CoV-2 vaccines in recipients of solid organ transplant: a systematic review …

K Manothummetha, N Chuleerarux… - JAMA network …, 2022 - jamanetwork.com
Importance Recipients of solid organ transplant (SOT) experience decreased
immunogenicity after COVID-19 vaccination. Objective To summarize current evidence on …

Comparison of SARS-CoV-2 antibody response 4 weeks after homologous vs heterologous third vaccine dose in kidney transplant recipients: a randomized clinical …

R Reindl-Schwaighofer, A Heinzel… - JAMA internal …, 2022 - jamanetwork.com
Importance Fewer than 50% of kidney transplant recipients (KTRs) develop antibodies
against the SARS-CoV-2 spike protein after 2 doses of an mRNA vaccine. Preliminary data …

Impaired humoral response in renal transplant recipients to SARS-CoV-2 vaccination with BNT162b2 (Pfizer-BioNTech)

J Korth, M Jahn, O Dorsch, OE Anastasiou… - Viruses, 2021 - mdpi.com
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has a major impact on
transplant recipients, with mortality rates up to 20%. Therefore, the effect of established …

[HTML][HTML] Review of early immune response to SARS-CoV-2 vaccination among patients with CKD

EJ Carr, A Kronbichler, M Graham-Brown… - Kidney international …, 2021 - Elsevier
The effects of the coronavirus disease-2019 (COVID-19) pandemic, particularly among
those with chronic kidney disease (CKD), who commonly have defects in humoral and …

Vaccination in patients with kidney failure: lessons from COVID-19

N Babel, C Hugo, TH Westhoff - Nature Reviews Nephrology, 2022 - nature.com
Infection is the second leading cause of death in patients with chronic kidney disease (CKD).
Adequate humoral (antibody) and cellular (T cell-driven) immunity are required to minimize …

[HTML][HTML] Weak antibody response to three doses of mRNA vaccine in kidney transplant recipients treated with belatacept

N Chavarot, A Morel, M Leruez-Ville, E Vilain… - American Journal of …, 2021 - Elsevier
Poor responses to mRNA COVID-19 vaccine have been reported after 2 vaccine injections
in kidney transplant recipients (KTRs) treated with belatacept. We analyzed the humoral …

[HTML][HTML] The global impact of COVID-19 on solid organ transplantation: two years into a pandemic

A Nimmo, D Gardiner, I Ushiro-Lumb, R Ravanan… - …, 2022 - journals.lww.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has had a major global
impact on solid organ transplantation (SOT). An estimated 16% global reduction in …

The RECOVAC immune-response study: the immunogenicity, tolerability, and safety of COVID-19 vaccination in patients with chronic kidney disease, on dialysis, or …

JSF Sanders, FJ Bemelman, AL Messchendorp… - …, 2022 - journals.lww.com
Background. In kidney patients COVID-19 is associated with severely increased morbidity
and mortality. A comprehensive comparison of the immunogenicity, tolerability, and safety of …

Immunological responses to SARS-CoV-2 vaccines in kidney transplant recipients

M Prendecki, T Thomson, CL Clarke, P Martin… - The Lancet, 2021 - thelancet.com
Data are shown as median with IQR. Statistical analysis is by MannWhitney test (A) or
KruskallWallis test with Dunns posthoc correction (B).(A) Kidney transplant recipients who …