Seasonality patterns are reported in various psychiatric disorders. The current paper
summarizes findings on brain adaptations associated with seasonal changes, factors that …

Highlights•Sleep and circadian rhythm disruption (SCRD) is a common comorbidity in
psychiatric disorders.•Common mechanisms may underlie SCRD and psychiatric disease …

Purpose.: The post-illumination pupil response (PIPR) has been quantified using four
metrics, but the spectral sensitivity of only one is known; here we determine the other three …

It is difficult to detect visual function deficits in patients at risk for glaucoma (glaucoma
suspects) and at early disease stages with conventional ophthalmic tests such as perimetry …

In healthy humans, seasonality has been documented in psychological variables,
chronotype, sleep, feeding, metabolic and autonomic function, thermoregulation …

In two recent reports, melanopsin gene variations were associated with seasonal affective
disorder (SAD), and in changes in the timing of sleep and activity in healthy individuals. New …

Intrinsically photosensitive retinal ganglion cells (ipRGCs) are the most recently discovered
photoreceptor class in the human retina. This Element integrates new knowledge and …

Abstract Study Objectives: Individual differences in sleep timing have been widely
recognized and are of particular relevance in adolescents and young adults who often show …

Diurnal preference, or chronotype, determined partly by genetics and modified by age,
activity, and the environment, defines the time of day at which one feels at his/her best, when …

Schizophrenia has long been associated with abnormalities in circadian rhythms and sleep.
Up until now, there have been no thorough reviews of the potential mechanisms behind the …