The cross-talk between gut microbiota and lungs in common lung diseases

D Zhang, S Li, N Wang, HY Tan, Z Zhang… - Frontiers in …, 2020 - frontiersin.org
Emerging findings indicate there is a vital cross-talk between gut microbiota and the lungs,
which is known as gut–lung axis. The gut disturbances in lung diseases including allergy …

Human gut microbiome: function matters

A Heintz-Buschart, P Wilmes - Trends in microbiology, 2018 - cell.com
The human gut microbiome represents a complex ecosystem contributing essential
functions to its host. Recent large-scale metagenomic studies have provided insights into its …

The gut-lung axis in cystic fibrosis

CE Price, GA O'Toole - Journal of bacteriology, 2021 - Am Soc Microbiol
Cystic fibrosis (CF) is a heritable, multiorgan disease that impacts all tissues that normally
express cystic fibrosis transmembrane conductance regulator (CFTR) protein. While the …

Applications of tandem mass spectrometry (MS/MS) in protein analysis for biomedical research

AN Neagu, M Jayathirtha, E Baxter, M Donnelly… - Molecules, 2022 - mdpi.com
Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of
methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted …

Impact of CFTR modulation with ivacaftor on gut microbiota and intestinal inflammation

CY Ooi, SA Syed, L Rossi, M Garg, B Needham… - Scientific reports, 2018 - nature.com
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance
regulator (CFTR) gene. Next to progressive airway disease, CF is also associated with …

Gut microbiota in children with cystic fibrosis: a taxonomic and functional dysbiosis

MJ Coffey, S Nielsen, B Wemheuer, NO Kaakoush… - Scientific Reports, 2019 - nature.com
Intestinal dysbiosis has been observed in children with cystic fibrosis (CF), yet the functional
consequences are poorly understood. We investigated the functional capacity of intestinal …

Cystic fibrosis-related gut dysbiosis: a systematic review

LR Caley, H White, MC de Goffau, RA Floto… - Digestive Diseases and …, 2023 - Springer
Abstract Background and Aims Cystic Fibrosis (CF) is associated with gut dysbiosis, local
and systemic inflammation, and impaired immune function. Gut microbiota dysbiosis results …

Unipept 4.0: functional analysis of metaproteome data

R Gurdeep Singh, A Tanca, A Palomba… - Journal of proteome …, 2018 - ACS Publications
Unipept (https://unipept. ugent. be) is a web application for metaproteome data analysis, with
an initial focus on tryptic-peptide-based biodiversity analysis of MS/MS samples. Because …

Fecal dysbiosis in infants with cystic fibrosis is associated with early linear growth failure

HS Hayden, A Eng, CE Pope, MJ Brittnacher, AT Vo… - Nature medicine, 2020 - nature.com
Most infants with cystic fibrosis (CF) have pancreatic exocrine insufficiency that results in
nutrient malabsorption and requires oral pancreatic enzyme replacement. Newborn …

Intestinal inflammation and alterations in the gut microbiota in cystic fibrosis: a review of the current evidence, pathophysiology and future directions

RY Tam, JM van Dorst, I McKay, M Coffey… - Journal of clinical …, 2022 - mdpi.com
Cystic fibrosis (CF) is a life-limiting autosomal recessive multisystem disease. While its
burden of morbidity and mortality is classically associated with pulmonary disease, CF also …