Large bone defects are a major global health concern. Bone tissue engineering (BTE) is the
most promising alternative to avoid the drawbacks of autograft and allograft bone …

3D printed/bioprinted tissue constructs are being used in vitro models and for the
regeneration of damaged tissues. Most of the fabricated 3D constructs fail to undergo …

The aim of osteochondral tissue engineering is to achieve the complex, functional and three-
dimensional tissue regeneration under well defined, controlled and reproducible conditions …

The craniofacial region consists of several different tissue types. These tissues are quite
commonly affected by traumatic/pathologic tissue loss which has so far been traditionally …

It has been observed that bone fractures carry a risk of high mortality and morbidity. The
deployment of a proper bone healing method is essential to achieve the desired success …

Bioreactor systems are very precious tools to generate living bone grafts in vitro. The aim of
this study was to compare the effectiveness of rotating and perfusion bioreactor in the …

Accurate repair of osteochondral defects is a great challenge due to the complex structure of
osteochondral defects. The current study aims to prepare a biomimetic osteochondral …

Extracellular matrix (ECM)-contained grafts can be achieved by decellularization of native
bones or synthetic scaffolds. Limitations associated with harvesting the native bone has …

Bone is a dynamic environment where osteocytes, osteoblasts, and mesenchymal
stem/progenitor cells perceive mechanical cues and regulate bone metabolism accordingly …

Objective This systematic review evaluates the purpose, materials, physio-mechanical, and
biological effects of bilayer scaffolds/membranes used for bone tissue engineering …