The renin–angiotensin system (RAS) was initially considered to be part of the endocrine
system regulating water and electrolyte balance, systemic vascular resistance, blood …

Alzheimer's disease (AD) is a well-known neurodegenerative disease characterized by the
presence of two main hallmarks–Tau hyperphosphorylation and Aβ deposits …

Emotional disorders, including depression and anxiety, contribute considerably to morbidity
across the world. Depression is a serious condition and is projected to be the top contributor …

Microglia are the primary resident retinal macrophages that monitor neuronal activity in real-
time and facilitate angiogenesis during retinal development. In certain retinal diseases, the …

Summary Na+/K+-ATPase (NKA) plays an important role in the central nervous system.
However, little is known about its function in the microglia. Here, we found that NKAα1 forms …

Introduction Neuroinflammation and autophagy are implicated in stress-related major
depressive disorder (MDD), but the underlying molecular mechanisms remain largely …

Objective Bexarotene treatments exert neuroprotective effects on mice following traumatic
brain injury (TBI). The present study aims to investigate the potential roles of the long …

Depression is a mood disorder characterized by abnormal thoughts. The pathophysiology of
depression is related to the deficiency of serotonin (5HT), which is derived from tryptophan …

Clinical studies demonstrated a positive correlation between hypertension and cognitive
decline. Beneficial effects of angiotensin II receptor blockers on cognitive functions have …

Aims Alzheimer's disease (AD) pathology is associated with brain inflammation involving
microglia and astrocytes. The renin‐angiotensin system contributes to brain inflammation …