Evolutionary trajectory of SARS-CoV-2 and emerging variants

J Singh, P Pandit, AG McArthur, A Banerjee… - Virology journal, 2021 - Springer
The emergence of a novel coronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), and more recently, the independent evolution of multiple SARS-CoV-2 …

Natural products as potential lead compounds to develop new antiviral drugs over the past decade

JH Zhao, YW Wang, J Yang, ZJ Tong, JZ Wu… - European Journal of …, 2023 - Elsevier
Virus infection has been one of the main causes of human death since the ancient times.
Even though more and more antiviral drugs have been approved in clinic, long-term use can …

COVID-19: comprehensive review on mutations and current vaccines

AV Hebbani, S Pulakuntla, P Pannuru… - Archives of …, 2022 - Springer
Viral outbreaks had been a threat for the human race for a long time. Several epidemics and
pandemics have been reported in the past with serious consequences on human health and …

Human coronavirus OC43 as a low-risk model to study COVID-19

MI Kim, C Lee - Viruses, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic has had irreversible and devastating
impacts on every aspect of human life. To better prepare for the next similar pandemic, a …

The novel insight of SARS-CoV-2 molecular biology and pathogenesis and therapeutic options

A Asghari, M Naseri, H Safari, E Saboory… - DNA and Cell …, 2020 - liebertpub.com
On December 31, 2019, a novel coronavirus, being the third highly infective CoV and named
as coronavirus disease 2019 (COVID-19) in the city of Wuhan, was announced by the World …

Computational investigation of natural compounds as potential main protease (Mpro) inhibitors for SARS-CoV-2 virus

CN Patel, SP Jani, SP Kumar, KM Modi… - Computers in Biology and …, 2022 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is significantly impacting human lives …

Large-scale recombinant production of the SARS-CoV-2 proteome for high-throughput and structural biology applications

N Altincekic, SM Korn, NS Qureshi… - Frontiers in molecular …, 2021 - frontiersin.org
The highly infectious disease COVID-19 caused by the Betacoronavirus SARS-CoV-2 poses
a severe threat to humanity and demands the redirection of scientific efforts and criteria to …

Human coronaviruses do not transfer efficiently between surfaces in the absence of organic materials

M Dallner, J Harlow, N Nasheri - Viruses, 2021 - mdpi.com
Human coronaviruses, including SARS-CoV-2, are known to spread mainly via close contact
and respiratory droplets. However, other potential means of transmission may be present …

Virome of high-altitude canine digestive tract and genetic characterization of novel viruses potentially threatening human health

X Jiang, J Liu, Y Xi, Q Zhang, Y Wang, M Zhao, X Lu… - Msphere, 2023 - Am Soc Microbiol
The majority of currently emerging infectious illnesses are zoonotic infections, which have
caused serious public health and economic implications. The development of viral …

The role of Bcl-xL protein in viral infections

Z Wyżewski, W Świtlik, MB Mielcarska… - International Journal of …, 2021 - mdpi.com
Bcl-xL represents a family of proteins responsible for the regulation of the intrinsic apoptosis
pathway. Due to its anti-apoptotic activity, Bcl-xL co-determines the viability of various virally …