Mitochondria: The Hub of Cellular Ca2+ Signaling
G Szabadkai, MR Duchen - Physiology, 2008 - journals.physiology.org
Mitochondria couple cellular metabolic state with Ca2+ transport processes. They therefore
control not only their own intra-organelle [Ca2+], but they also influence the entire cellular …
control not only their own intra-organelle [Ca2+], but they also influence the entire cellular …
Mitochondrial SLC25 carriers: novel targets for cancer therapy
The transfer of metabolites through the mitochondrial membranes is a vital process that is
highly controlled and regulated by the inner membrane. A variety of metabolites …
highly controlled and regulated by the inner membrane. A variety of metabolites …
Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli
K Imamura, N Imamachi, G Akizuki, M Kumakura… - Molecular cell, 2014 - cell.com
Although thousands of long noncoding RNAs (lncRNAs) are localized in the nucleus, only a
few dozen have been functionally characterized. Here we show that nuclear enriched …
few dozen have been functionally characterized. Here we show that nuclear enriched …
The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffold
Nuclear proteins are often given a concise title that captures their function, such as
'transcription factor,''polymerase'or 'nuclear-receptor.'However, for members of the …
'transcription factor,''polymerase'or 'nuclear-receptor.'However, for members of the …
The mitochondrial citrate carrier: a new player in inflammation
The mitochondrial CIC (citrate carrier) catalyses the efflux of citrate from the mitochondrial
matrix in exchange for cytosolic malate. In the present paper we show that CIC mRNA and …
matrix in exchange for cytosolic malate. In the present paper we show that CIC mRNA and …
A key role of the mitochondrial citrate carrier (SLC25A1) in TNFα-and IFNγ-triggered inflammation
V Infantino, V Iacobazzi, A Menga… - … et Biophysica Acta (BBA …, 2014 - Elsevier
The chronic induction of inflammation underlies multiple pathological conditions, including
metabolic, autoimmune disorders and cancer. The mitochondrial citrate carrier (CIC) …
metabolic, autoimmune disorders and cancer. The mitochondrial citrate carrier (CIC) …
Loss of Sfpq causes long-gene transcriptopathy in the brain
A Takeuchi, K Iida, T Tsubota, M Hosokawa, M Denawa… - Cell Reports, 2018 - cell.com
Genes specifically expressed in neurons contain members with extended long introns.
Longer genes present a problem with respect to fulfilment of gene length transcription, and …
Longer genes present a problem with respect to fulfilment of gene length transcription, and …
[HTML][HTML] Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage …
The mitochondrial citrate–malate exchanger (CIC), a known target of acetylation, is up-
regulated in activated immune cells and plays a key role in the production of inflammatory …
regulated in activated immune cells and plays a key role in the production of inflammatory …
Pistacia lentiscus Hydrosol: Untargeted Metabolomic Analysis and Anti‐Inflammatory Activity Mediated by NF‐κB and the Citrate Pathway
A Santarsiero, A Onzo, R Pascale… - Oxidative medicine …, 2020 - Wiley Online Library
Pistacia lentiscus shows a long range of biological activities, and it has been used in
traditional medicine for treatment of various kinds of diseases. Moreover, related essential …
traditional medicine for treatment of various kinds of diseases. Moreover, related essential …
Long non-coding RNAs involved in immune responses
K Imamura, N Akimitsu - Frontiers in immunology, 2014 - frontiersin.org
A large number of human RNA transcripts, which do not encode proteins are defined as non-
coding RNAs (ncRNAs). These ncRNAs are divided into two classes of different lengths; …
coding RNAs (ncRNAs). These ncRNAs are divided into two classes of different lengths; …