Pharmacokinetics of magnetic iron oxide nanoparticles for medical applications

J Nowak-Jary, B Machnicka - Journal of Nanobiotechnology, 2022 - Springer
Magnetic iron oxide nanoparticles (MNPs) have been under intense investigation for at least
the last five decades as they show enormous potential for many biomedical applications …

Scavenger receptor structure and function in health and disease

I Abdul Zani, SL Stephen, NA Mughal, D Russell… - Cells, 2015 - mdpi.com
Scavenger receptors (SRs) are a 'superfamily'of membrane-bound receptors that were
initially thought to bind and internalize modified low-density lipoprotein (LDL), though it is …

[HTML][HTML] Efficient production and enhanced tumor delivery of engineered extracellular vesicles

DC Watson, D Bayik, A Srivatsan, C Bergamaschi… - Biomaterials, 2016 - Elsevier
Extracellular vesicles (EV), including exosomes and microvesicles, are nano-sized
intercellular communication vehicles that participate in a multitude of physiological …

Fucoidan and cancer: A multifunctional molecule with anti-tumor potential

F Atashrazm, RM Lowenthal, GM Woods, AF Holloway… - Marine drugs, 2015 - mdpi.com
There is a wide variety of cancer types yet, all share some common cellular and molecular
behaviors. Most of the chemotherapeutic agents used in cancer treatment are designed to …

Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

DR Getts, AJ Martin, DP McCarthy, RL Terry… - Nature …, 2012 - nature.com
Aberrant T-cell activation underlies many autoimmune disorders, yet most attempts to induce
T-cell tolerance have failed. Building on previous strategies for tolerance induction that …

Formation and maturation of the phagosome: a key mechanism in innate immunity against intracellular bacterial infection

HJ Lee, Y Woo, TW Hahn, YM Jung, YJ Jung - Microorganisms, 2020 - mdpi.com
Phagocytosis is an essential mechanism in innate immune defense, and in maintaining
homeostasis to eliminate apoptotic cells or microbes, such as Mycobacterium tuberculosis …

Fucoidan from Macrocystis pyrifera Has Powerful Immune-Modulatory Effects Compared to Three Other Fucoidans

W Zhang, T Oda, Q Yu, JO Jin - Marine drugs, 2015 - mdpi.com
Fucoidan, a sulfated polysaccharide purified from brown algae, has a variety of immune-
modulation effects, such as promoting activation of dendritic cells (DCs), natural killer (NK) …

Current development of nano-drug delivery to target macrophages

D Cai, W Gao, Z Li, Y Zhang, L Xiao, Y Xiao - Biomedicines, 2022 - mdpi.com
Macrophages are the most important innate immune cells that participate in various
inflammation-related diseases. Therefore, macrophage-related pathological processes are …

Fucoidan can function as an adjuvant in vivo to enhance dendritic cell maturation and function and promote antigen-specific T cell immune responses

JO Jin, W Zhang, JY Du, KW Wong, T Oda, Q Yu - PloS one, 2014 - journals.plos.org
Fucoidan, a sulfated polysaccharide purified from brown algae, has a variety of immune-
modulation effects, including promoting antigen uptake and enhancing anti-viral and anti …

[HTML][HTML] Scavenger receptor MARCO contributes to macrophage phagocytosis and clearance of tumor cells

Q Xing, Y Feng, H Sun, S Yang, T Sun, X Guo… - Experimental Cell …, 2021 - Elsevier
Macrophage receptor with collagenous structure (MARCO) is a member of the class A
scavenger receptor family which is expressed on the cell surface of macrophages. It is well …