Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

Highlights•The human microbiota plays a pivotal role in protection against Candida
infections.•Bacterial metabolites influence the virulence of fungi via diverse …

Most microbes have developed responses that protect them against stresses relevant to
their niches. Some that inhabit reasonably predictable environments have evolved …

C-type lectin receptors (CLRs) expressed by myeloid cells constitute a versatile family of
receptors that play a key role in innate immune recognition. Myeloid CLRs exhibit a …

Microbial species capable of co-existing with healthy individuals, such as the commensal
fungus Candida albicans, exploit multifarious strategies to evade our immune defenses …

SUMMARY A significant increase in the incidence of Candida-mediated infections has been
observed in the last decade, mainly due to rising numbers of susceptible individuals …

The human gastrointestinal microbiome encompasses bacteria, fungi, and viruses forming
complex bionetworks which, for organismal health, must be in a state of homeostasis. An …

Invasive fungal infections are rapidly increasing, and the opportunistic pathogenic Candida
species are the fourth most common cause of nosocomial systemic infections. The current …

The fungal community of the skin microbiome is dominated by a single genus, Malassezia.
Besides its symbiotic lifestyle at the host interface, this commensal yeast has also been …

The intestinal microbiome harbors fungi that pose a significant risk to human health as
opportunistic pathogens and drivers of inflammation. Inflammatory and autoimmune …