Recent advances in the synthesis of diarylheptanoids

K Sudarshan, S Yarlagadda… - Chemistry–An Asian …, 2024 - Wiley Online Library
In the quest for synthesizing biologically important natural products, medicinal chemists
embark on an endless journey. This review focuses on the reports published towards the …

Diarylheptanoid: A privileged structure in drug discovery

DJ Sun, LJ Zhu, YQ Zhao, YQ Zhen, L Zhang, CC Lin… - Fitoterapia, 2020 - Elsevier
Privileged structures are widely used in the process of drug design, and provide an effective
template in medicinal chemistry. Diarylheptanoids are a class of structurally distinctive …

Medicinal plants with potential inhibitory bioactive compounds against coronaviruses

OA Adeleye, OA Bamiro, LG Bakre… - Advanced …, 2021 - pmc.ncbi.nlm.nih.gov
Medicinal plant is a major source of drug discovery for disease management. Over 85% of
the population in Asia and in the Middle East use herbal medicine for disease management …

Recent studies on cyclic 1, 7-diarylheptanoids: their isolation, structures, biological activities, and chemical synthesis

Y Jahng, JG Park - Molecules, 2018 - mdpi.com
Diarylheptanoids are a family of plant secondary metabolites with a 7 carbon skeleton
possessing two phenyl rings at the 1-and 7-positions. They can be subdivided into acyclic …

Investigation of Major Flavonoids from Artemisia argyi as a Potential COVID-19 Drug: Molecular Docking and DFT Calculations

Y Lu, B Zhang, N Wang, M Li, N Xi - Crystals, 2022 - mdpi.com
Flavonoids from natural products are well-identified as potential antiviral agents in the
treatment of SARS-CoV-2 (COVID-19) infection and related diseases. However, some major …

In-vitro anticancer activity of chemical constituents from etlingera alba poulsen against triple negative breast cancer and in silico approaches towards matrix …

W Wahyuni, A Diantini, M Ghozali… - Indonesian Journal of …, 2022 - ejournal.kjpupi.id
Etlingera alba (EA) is one of the endemic plants grown in Sulawesi. We determined the
cytotoxic and anti-metastatic activity of isolates obtained from EA rhizome extract. IC50 value …

Exploring the DNA-binding and anticancer potential of polypyridyl ruthenium (II) complexes

D Zhang, M Li, AFMM Rahman, Z Liu, Y Lu - Journal of Molecular Structure, 2025 - Elsevier
Organometallic medicines based on ruthenium (Ru) have attracted interest as
chemotherapeutic and bioimaging agents due to their low toxicity and superior physical …

Long and short-term metformin consumption as a potential therapy to prevent complications of COVID-19

E Shaseb, S Ghaffary, A Garjani… - Advanced …, 2022 - pmc.ncbi.nlm.nih.gov
Purpose: The aim of the study is to evaluate the effect of metformin in complication
improvement of hospitalized patients with COVID-19. Methods: This was a randomized …

Quantification of flavonoids in alpinia officinarum hance. via HPLC and evaluation of its cytotoxicity on human prostate carcinoma (LNCaP) and breast carcinoma …

S Kazemi, F Asadi, L Barari… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Background: Various plant species have been shown to be effective in the prevention or
adjuvant therapy of cancer. Alpinia officinarum and its main phytochemicals have also been …

Isolation and identification of compounds from the resinous exudate of Escallonia illinita Presl. and their anti-oomycete activity

I Montenegro, E Sánchez, E Werner, P Godoy, Y Olguín… - BMC chemistry, 2019 - Springer
The resinous exudates from Escallonia illinita by products was characterized by FT-IR, NMR
and HRMS. Six compounds were isolated and identified as follows: 1, 5-diphenylpent-1-en …