Laminitis, one of the most debilitating conditions of all equids, is now known to be the result
of several systemic disease entities. This finding, together with other recent developments in …

With the increasing number of studies being published on the different experimental models
used to induce and study acute laminitis, the pathophysiological events associated with …

Laminitis in equids is a clinical syndrome usually associated with systemic disease.
Endocrinopathies recently have been recognized as the most common cause of laminitis …

Background Pituitary pars intermedia dysfunction (PPID) is a commonly described
endocrine disorder in higher latitudes of the Northern hemisphere but the description of the …

Background Several tests have been evaluated in horses for quantifying insulin
dysregulation to support a diagnosis of equine metabolic syndrome. Comparing the …

Reasons for performing study Hoof lamellar pathology in horses with pituitary pars
intermedia dysfunction (PPID) has not been described previously. Objectives To describe …

Until the turn of the millennium, laminitis was largely considered a discrete disease entity
with a common pathophysiology, regardless of the inciting cause. Ischemia was implicated …

Lamellar pathology in experimentally-induced equine laminitis associated with euglycaemic
hyperinsulinaemia is substantial by the acute, clinical phase (∼ 48h post-induction) …

Laminitis has many triggers and comparing the histopathology of lesions induced by
different causes may help to establish whether a common mechanism or multiple …

Equine metabolic syndrome is characterized by obesity and regional adiposity coupled with
evidence of recurrent laminitis. Although inflammation has been well characterized in …