Selenium nanoparticles as a nutritional supplement

S Skalickova, V Milosavljevic, K Cihalova, P Horky… - Nutrition, 2017 - Elsevier
Selenium is an essential trace element in the diet, required for maintenance of health and
growth; however, its toxicity could cause serious damage depending on dose and chemical …

Progress in brain targeting drug delivery system by nasal route

AR Khan, M Liu, MW Khan, G Zhai - Journal of Controlled Release, 2017 - Elsevier
The blood–brain barrier (BBB) restricts the transport of potential therapeutic moieties to the
brain. Direct targeting the brain via olfactory and trigeminal neural pathways by passing the …

Does the use of chitosan contribute to oxalate kidney stone formation?

MF Queiroz, KR Teodosio Melo, DA Sabry, GL Sassaki… - Marine drugs, 2014 - mdpi.com
Chitosan is widely used in the biomedical field due its chemical and pharmacological
properties. However, intake of chitosan results in renal tissue accumulation of chitosan and …

Biodegradable polymer nanogels for drug/nucleic acid delivery

Y Li, D Maciel, J Rodrigues, X Shi, H Tomás - Chemical reviews, 2015 - ACS Publications
Despite the extensive research on therapeutic delivery, many problems still exist on how to
develop a proper platform (a carrier) that can deliver drugs/nucleic acids to specific sites of …

Oral delivery of biologics for precision medicine

M Durán‐Lobato, Z Niu, MJ Alonso - Advanced Materials, 2020 - Wiley Online Library
The emerging field of precision medicine is rapidly growing, fostered by the advances in
genome mapping and molecular diagnosis. In general, the translation of these advances …

Enhanced antitumor immunity by targeting dendritic cells with tumor cell lysate-loaded chitosan nanoparticles vaccine

GN Shi, CN Zhang, R Xu, JF Niu, HJ Song, XY Zhang… - Biomaterials, 2017 - Elsevier
Whole tumor cell lysates (TCL) have been implemented as tumor antigens for cancer
vaccine development, although clinical outcomes of TCL-based antitumor immunotherapy …

Degradable polymeric bio (nano) materials and their biomedical applications: A comprehensive overview and recent updates

K Kuperkar, LI Atanase, A Bahadur, IC Crivei… - Polymers, 2024 - mdpi.com
Degradable polymers (both biomacromolecules and several synthetic polymers) for
biomedical applications have been promising very much in the recent past due to their low …

Epigallocatechin gallate: Phytochemistry, bioavailability, utilization challenges, and strategies

S Mehmood, M Maqsood, N Mahtab… - Journal of Food …, 2022 - Wiley Online Library
Epigallocatechin gallate (EGCG), a green tea catechin, has gained the attention of current
study due to its excellent health‐promoting effects. It possesses anti‐obesity, antimicrobial …

Polymeric nano-and microparticulate drug delivery systems for treatment of biofilms

SE Birk, A Boisen, LH Nielsen - Advanced Drug Delivery Reviews, 2021 - Elsevier
Now-a-days healthcare systems face great challenges with antibiotic resistance and low
efficacy of antibiotics when combating pathogenic bacteria and bacterial biofilms …

Chitosan for gene delivery: Methods for improvement and applications

D Chuan, T Jin, R Fan, L Zhou, G Guo - Advances in colloid and interface …, 2019 - Elsevier
Gene therapy is a promising strategy for treating challenging diseases. The successful
delivery of genes is a critical step for gene therapy. However, concerns about …