The emergence, genomic diversity and global spread of SARS-CoV-2

J Li, S Lai, GF Gao, W Shi - Nature, 2021 - nature.com
Since the first cases of COVID-19 were documented in Wuhan, China in 2019, the world has
witnessed a devastating global pandemic, with more than 238 million cases, nearly 5 million …

The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

[HTML][HTML] Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2

P Han, L Li, S Liu, Q Wang, D Zhang, Z Xu, P Han, X Li… - Cell, 2022 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic continues worldwide with
many variants arising, some of which are variants of concern (VOCs). A recent VOC, omicron …

[HTML][HTML] Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based …

M Antonelli, RS Penfold, J Merino… - The Lancet Infectious …, 2022 - thelancet.com
Background COVID-19 vaccines show excellent efficacy in clinical trials and effectiveness in
real-world data, but some people still become infected with SARS-CoV-2 after vaccination …

Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape

JS Tregoning, KE Flight, SL Higham, Z Wang… - Nature reviews …, 2021 - nature.com
Where 2020 saw the development and testing of vaccines against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) at an unprecedented pace, the first half of 2021 has …

After the pandemic: perspectives on the future trajectory of COVID-19

A Telenti, A Arvin, L Corey, D Corti, MS Diamond… - Nature, 2021 - nature.com
There is a realistic expectation that the global effort in vaccination will bring the pandemic
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) under control …

Tackling COVID-19 with neutralizing monoclonal antibodies

D Corti, LA Purcell, G Snell, D Veesler - Cell, 2021 - cell.com
Monoclonal antibodies (mAbs) have revolutionized the treatment of several human
diseases, including cancer and autoimmunity and inflammatory conditions, and represent a …

[HTML][HTML] Novel SARS-CoV-2 variants: the pandemics within the pandemic

E Boehm, I Kronig, RA Neher, I Eckerle, P Vetter… - Clinical Microbiology …, 2021 - Elsevier
Background Many new variants of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have been termed variants of concern/interest (VOC/I) because of the greater …

[PDF][PDF] COVID-19 weekly epidemiological update, edition 43, 8 June 2021

World Health Organization - 2021 - apps.who.int
Global case and death incidences continued to decrease with over 3 million new weekly
cases and over 73 000 new deaths, a 15% and an 8% decrease respectively, compared to …

Variant-specific symptoms of COVID-19 in a study of 1,542,510 adults in England

M Whitaker, J Elliott, B Bodinier, W Barclay… - Nature …, 2022 - nature.com
Infection with SARS-CoV-2 virus is associated with a wide range of symptoms. The REal-
time Assessment of Community Transmission− 1 (REACT-1) study monitored the spread …