Acetylcholinesterase (AChE) holds significance in Alzheimer's disease (AD), where
cognitive impairment correlates with insufficient acetylcholine levels. AChE's role involves …

This study employs a comprehensive approach combining protein retrieval, sequence
alignment, and molecular dynamics simulations to investigate the structural dynamics and …

Background Breast cancer (BC) is the most frequent malignancy in the world. Chemotherapy
(CT) is a common treatment for BC but is accompanied by toxicity and side effects. Shenqi …

Non-small cell lung cancer (NSCLC) is among the main causes of mortality from cancer
around the globe, affecting all genders. Current treatments mainly focus on tyrosine kinase …

Triple-negative breast cancer (TNBC) is considered to be one of the most difficult subtypes
of breast cancer (BC) to treat. The sheer absence of certain receptors makes it very tough to …

The exploration of potential candidates for fungicides against four fungal proteins that cause
some vital plant diseases, namely Phytophthora capsici, Botrytis cinerea, Fusarium …

Attention-deficit/hyperactivity disorder (ADHD) is a persistent neurodevelopmental disorder.
Despite pharmacological interventions, there is a need for effective lead molecules and …

Dengue fever is a significant global public health concern, causing substantial morbidity and
mortality worldwide. The disease can manifest in various forms, from mild fever to potentially …

Due to the multifarious nature of cancer, finding a single definitive cure for this dreadful
disease remains an elusive challenge. The dysregulation of the apoptotic pathway or …

Cancers and tumors grow day by day and alternate traditional-based medicines are in
demand to nullify the toxicity and side effects caused by modern pharmacological …