Significance of long chain polyunsaturated fatty acids in human health

R Zárate, N el Jaber-Vazdekis, N Tejera… - Clinical and translational …, 2017 - Springer
In the last decades, the development of new technologies applied to lipidomics has
revitalized the analysis of lipid profile alterations and the understanding of the underlying …

Coriander (Coriandrum sativum): A promising functional food toward the well-being

V Prachayasittikul, S Prachayasittikul… - Food Research …, 2018 - Elsevier
Coriandrum sativum (C. sativum) or coriander is one of the most popularly used spices in
culinary worldwide, and its medicinal values has been recognized since ancient time. C …

Neurobiological links between depression and AD: the role of TGF-β1 signaling as a new pharmacological target

F Caraci, SF Spampinato, MG Morgese… - Pharmacological …, 2018 - Elsevier
In the last several years a large number of studies have demonstrated the neurobiological
and clinical continuum between depression and Alzheimer's disease (AD). Depression is a …

Resveratrol and depression in animal models: a systematic review of the biological mechanisms

A Moore, J Beidler, MY Hong - Molecules, 2018 - mdpi.com
Depression is currently treated by pharmacotherapies that can elicit debilitating side effects
for patients. Novel treatment options with limited side effects are currently being researched …

Exposure to As-, Cd-, and Pb-mixture induces Aβ, amyloidogenic APP processing and cognitive impairments via oxidative stress-dependent neuroinflammation in …

A Ashok, NK Rai, S Tripathi… - Toxicological …, 2015 - academic.oup.com
Environmental pollutants act as risk factors for Alzheimer's disease (AD), mainly affecting the
aging population. We investigated early manifestations of AD-like pathology by a mixture of …

Depression in Alzheimer's disease: epidemiology, mechanisms, and management

S Chi, JT Yu, MS Tan, L Tan - Journal of Alzheimer's disease, 2014 - content.iospress.com
Depression occurs with a high prevalence of up to 50% in patients with Alzheimer's disease
(AD) and increases the caregivers' burden. Depression symptoms can precede clinical …

Neurotrophins role in depression neurobiology: a review of basic and clinical evidence

FL Neto, G Borges, S Torres-Sanchez… - Current …, 2011 - ingentaconnect.com
Depression is a neuropsychiatric disorder affecting a huge percentage of the active
population especially in developed countries. Research has devoted much of its attention to …

Silibinin ameliorates anxiety/depression-like behaviors in amyloid β-treated rats by upregulating BDNF/TrkB pathway and attenuating autophagy in hippocampus

X Song, B Liu, L Cui, B Zhou, W Liu, F Xu… - Physiology & …, 2017 - Elsevier
Depression is one of the most frequent psychiatric disorders of Alzheimer's disease (AD).
Depression and anxiety are associated with increased risk of developing AD. Silibinin, a …

Design and development of benzyl piperazine linked 5-phenyl-1, 2, 4-triazole-3-thione conjugates as potential agents to combat Alzheimer's disease

PVR Kiran, DK Waiker, A Verma, P Saraf… - Bioorganic …, 2023 - Elsevier
Our present work demonstrates the molecular hybridization-assisted design, synthesis, and
biological evaluation of 22 benzylpiperazine-linked 1, 2, 4-triazole compounds (PD1-22) as …

Antioxidant activity of fluoxetine and vortioxetine in a non-transgenic animal model of alzheimer's disease

G Caruso, M Grasso, A Fidilio, SA Torrisi… - Frontiers in …, 2021 - frontiersin.org
Depression is a risk factor for the development of Alzheimer's disease (AD). A
neurobiological and clinical continuum exists between AD and depression, with …