Risk assessment of glycoalkaloids in feed and food, in particular in potatoes and potato‐derived products

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific opinion on the risks for
animal and human health related to the presence of glycoalkaloids (GA s) in feed and food …

Predisposing factors of type 2 diabetes mellitus and the potential protective role of native plants with functional properties

C Njume, O Donkor, AJ McAinch - Journal of Functional Foods, 2019 - Elsevier
Type 2 diabetes mellitus (T2DM) affects at least 285 million people globally and is at
epidemic proportions within Indigenous communities in Australia. This review creates …

The application of an aqueous two-phase system combined with ultrasonic cell disruption extraction and HPLC in the simultaneous separation and analysis of …

L Zhu, Y Lu, Z Sun, J Han, Z Tan - Food chemistry, 2020 - Elsevier
An aqueous two-phase system was used in conjunction with ultrasonic cell disruption to
extract and separate solanine (mainly solasonine and solamargine) and Solanum nigrum …

[HTML][HTML] Biophysical study of the non-steroidal anti-inflammatory drugs (NSAID) ibuprofen, naproxen and diclofenac with phosphatidylserine bilayer membranes

M Manrique-Moreno, L Heinbockel, M Suwalsky… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) represent an effective pain treatment option
and therefore one of the most sold therapeutic agents worldwide. The study of the molecular …

Membrane interaction of ibuprofen with cholesterol-containing lipid membranes

J Kremkow, M Luck, D Huster, P Müller, HA Scheidt - Biomolecules, 2020 - mdpi.com
Deciphering the membrane interaction of drug molecules is important for improving drug
delivery, cellular uptake, and the understanding of side effects of a given drug molecule. For …

[HTML][HTML] In vivo antihyperglycaemic and antihyperlipidemic activities and chemical constituents of Solanum anomalum

JE Okokon, IC Etuk, PS Thomas, FP Drijfhout… - Biomedicine & …, 2022 - Elsevier
Solanum anomalum is a plant used ethnomedically for the treatment of diabetes. The study
was aimed to validate ethnomedical claims in rat model and identify the likely antidiabetic …

The Impact of Steroidal Glycoalkaloids on the Physiology of Phytophthora infestans, the Causative Agent of Potato Late Blight

P Dahlin, MC Müller, S Ekengren… - Molecular plant …, 2017 - Am Phytopath Society
Steroidal glycoalkaloids (SGAs) are plant secondary metabolites known to be toxic to
animals and humans and that have putative roles in defense against pests. The proposed …

A Comprehensive Study on the Biological Activity of Elderberry Extract and Cyanidin 3-O-Glucoside and Their Interactions with Membranes and Human Serum …

P Strugała, S Loi, B Bażanów, P Kuropka… - Molecules, 2018 - mdpi.com
In our research we used the extract from dietary supplement of elderberry (EE) and its
dominant anthocyanin—cyanidin 3-O-glucoside (Cy 3-gluc). By interacting with a model …

[HTML][HTML] In vitro protective effects of resveratrol against oxidative damage in human erythrocytes

M Suwalsky, F Villena, MJ Gallardo - Biochimica et Biophysica Acta (BBA) …, 2015 - Elsevier
Resveratrol (RV) is a potent antioxidant, anticancer and anti-inflammatory agent. Its main
target of action is the cell membrane; however, its effect on that of human erythrocytes has …

Alkaloids modulate the functioning of ion channels produced by antimicrobial agents via an influence on the lipid host

SS Efimova, AA Zakharova… - Frontiers in Cell and …, 2020 - frontiersin.org
It is widely recognized that an alteration in membrane physical properties induced by the
adsorption of various drugs and biologically active compounds might greatly affect the …