As a versatile therapeutic modality, peptides attract much attention because of their great
binding affinity, low toxicity, and the capability of targeting traditionally “undruggable” protein …

This review covers some of the recent progress in the field of peptide antibiotics with a focus
on compounds with novel or established mode of action and with demonstrated efficacy in …

The microorganisms that have developed resistance to available therapeutic agents are
threatening the globe and multidrug resistance among the bacterial pathogens is becoming …

The natural antibiotic teixobactin kills pathogenic bacteria without detectable resistance. The
difficult synthesis and unfavourable solubility of teixobactin require modifications, yet …

Appearance of antibiotic resistance in bacteria is a convoluted topic, particularly in treating
pestiferous immunodeficiency correlated diseases. The main objective of the current …

Bacteria utilize multiple mechanisms that enable them to gain or acquire resistance to
antibiotic therapies during the treatment of infections. In addition, bacteria form biofilms …

Antimicrobial resistance is a serious threat to human health worldwide, prompting research
efforts on a massive scale in search of novel antibiotics to fill an urgent need for a remedy …

Antibiotics have served humankind through their use in modern medicine as effective
treatments for otherwise fatal bacterial infections. Teixobactin is a first member of newly …

Teixobactin represents a new class of antibiotics with novel structure and excellent activity
against Gram-positive pathogens and Mycobacterium tuberculosis. Herein, we report a one …

The discovery of antibiotics has led to the effective treatment of bacterial infections that were
otherwise fatal and has had a transformative effect on modern medicine. Teixobactin is an …