Carbodiimides are a unique class of heterocumulene compounds that display distinctive
chemical properties. The rich chemistry of carbodiimides has drawn increasing attention …

The discovery of nonproteinogenic amino acids among natural products, either in native
state or as fragments of complex molecules, has increased the level of interest in this family …

Natural and synthetic azetidinone derivatives occupy a central place among medicinally
important compounds due to their diverse and interesting antibiotic activities. 1–9 Even …

β-lactam ring-containing compounds such as penicillins, ampicillin, amoxicillin,
cephalosporins and carbapenem are among the most famous antibiotics. This article …

Carbon monoxide is an indispensable C1 building block that has been recognized as a
potent feedstock for synthesizing carbonyl-containing molecules. Carbonylative reactions …

Since the advent of penicillin, the β-lactam antibiotics have been the subject of much
discussion and investigation, within both the scientific and public sectors. The primary …

In the last two decades, the better understanding of the mechanistic aspects of the β-lactams'
biological activity and their inhibition, and the chemical exploitation of β-lactams as synthetic …

Azetidin-2-one, a four-membered cyclic lactam (β-lactam) skeleton has been recognised as
a useful building block for the synthesis of a large number of organic molecules by exploiting …

N-Heterocyclic carbene (NHC) has been employed as an efficient catalyst for ring expansion
of 4-formyl-β-lactams, allowing the facile synthesis of succinimide derivatives. This …

The first examples accounting for the catalytic deprotection of allylic amines by using
reagents different from palladium catalysts have been achieved via Grubbs' carbene …