Toll-like receptors (TLRs) are germline-encoded pattern recognition receptors (PRRs) that
play a central role in host cell recognition and responses to microbial pathogens. TLR …

Highlights•CLRs play an essential role in immunity to fungi and mycobacteria.•CLRs are
involved in the regulation of homeostasis, autoimmunity and allergy.•CLRs recognise and …

The innate immune system deploys a variety of pattern-recognition receptors (PRRs) which
include Toll-like receptors (TLRs), RIG-I-like receptors, NOD-like receptors, and C-type lectin …

Signalling C‐type lectin receptors (CLR s) are crucial in shaping the immune response to
fungal pathogens, but comparably little is known about the role of these receptors in …

Dectin-1 is an innate immune pattern recognition receptor (PRR) that, through its ability to
bind β-glucans, is involved in the recognition of several pathogenic fungi. Dectin-1 can …

Tuberculosis, an infectious disease caused by Mycobacterium tuberculosis (Mtb), remains a
major cause of human death worldwide. Innate immunity provides host defense against Mtb …

Mycobacterium tuberculosis (Mtb) infection is a major international public health problem.
One‐third of the world′ s population is thought to have latent tuberculosis, a condition …

CARD9 is a central component of anti-fungal innate immune signaling via C-type lectin
receptors, and several immune-related disorders are associated with CARD9 alterations …

Mycobacterium tuberculosis is an enormously successful human pathogen that can infect its
host for decades without causing clinical disease, only to reactivate when host immunity is …

Previous studies indicate that both Dectin-3 (also called MCL or Clec4d) and Mincle (also
called Clec4e), two C-type lectin receptors, can recognize trehalose 6, 6′-dimycolate …