• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Health professionals are encouraged to take the ESC Guidelines fully into account when
exercising their clinical judgment, as well as in the determination and the implementation of …

Left ventricular (LV) ejection fraction (LVEF) is a simple measure of global systolic function
that pervades the risk evaluation and management of many cardiovascular diseases …

Myocardial strain is a principle for quantification of left ventricular (LV) function which is now
feasible with speckle-tracking echocardiography. The best evaluated strain parameter is …

Advances in speckle-tracking echocardiography allowed the rise of deformation imaging as
a feasible, robust, and valuable tool for clinical routine. The global or segmental …

Background—Global longitudinal strain (GLS) is prognostic of adverse cardiovascular
outcomes in various patient populations, but the prognostic utility of GLS for long-term …

Background Noninvasive detection of functionally significant coronary artery disease (CAD)
by echocardiography remains challenging, with the need to perform stress imaging to detect …

Background Left ventricular ejection fraction (LVEF) is an established method for evaluation
of left ventricular (LV) systolic function. Global longitudinal strain (GLS) by speckle tracking …

Echocardiography is a reliable and reproducible method to assess non-invasively cardiac
function in clinical and experimental research. Significant progress in the development of …

Ischemic heart disease is a dynamic process of atherosclerosis of the coronary arteries or
functional alterations of coronary circulation that can be modified by lifestyle …