Understanding the biology underlying the mechanisms and pathways regulating pancreatic
β cell development is necessary to understand the pathology of diabetes mellitus (DM) …

Simple Summary This review highlights the scope of available treatment options for
neurological diseases, especially stem cell transplantation therapy, which provides new …

摘要目前已经认识到了各种类型早期发病的非自身免疫性糖尿病是单基因糖尿病,
每种亚型都是在个体水平上发生的高度变异的单一基因缺陷所导致的. 单基因糖尿病 …

Background Exosomes secreted from stem cells exerted salutary effects on the fibrotic liver.
Herein, the roles of exosomes derived from human embryonic stem cell (hESC) in anti …

Diabetes mellitus (DM) is one of the most prevalent metabolic disorders. In order to replace
the function of the destroyed pancreatic beta cells in diabetes, islet transplantation is the …

A stem cell is a particular group of cells that has the extraordinary potential to convert within
the body into particular cell types. They are used to regenerate tissues and cells in the body …

Abstract Background Pancreatic progenitors (PPs) co-expressing the two transcription
factors (TFs) PDX1 and NKX6. 1 are recognized as the indispensable precursors of …

Introduction Rigorous research in the last few years has shown that in addition to the
classical mechanism of neurodegeneration, certain unconventional mechanisms may also …

Background: Diabetes is a chronic metabolic disorder having a global prevalence of nearly
doubled over the last 30 years and has become one of the major health concerns …

Success in the differentiating human embryonic stem cells (hESCs) into insulin-secreting β
cells raises new hopes for diabetes treatment. In this work, we demonstrated the feasibility of …