Norepinephrine: a neuromodulator that boosts the function of multiple cell types to optimize CNS performance

J O'Donnell, D Zeppenfeld, E McConnell, S Pena… - Neurochemical …, 2012 - Springer
Norepinephrine (NE) is a neuromodulator that in multiple ways regulates the activity of
neuronal and non-neuronal cells. NE participates in the rapid modulation of cortical circuits …

The effects of acute stress and stress hormones on social cognition and behavior: current state of research and future directions

B von Dawans, J Strojny, G Domes - Neuroscience & Biobehavioral …, 2021 - Elsevier
Stress encompasses profound psychological and physiological changes that are observable
on all levels, from cellular mechanisms, humoral changes, and brain activation to subjective …

Brain plasticity and functional losses in the aged: scientific bases for a novel intervention

HW Mahncke, A Bronstone, MM Merzenich - Progress in brain research, 2006 - Elsevier
Aging is associated with progressive losses in function across multiple systems, including
sensation, cognition, memory, motor control, and affect. The traditional view has been that …

Stress hormones and human memory function across the lifespan

SJ Lupien, A Fiocco, N Wan, F Maheu, C Lord… - …, 2005 - Elsevier
In this paper, we summarize the data obtained in our laboratory showing the effects of
glucocorticoids on human cognitive function in older adults, young adults and children. We …

There and back again: a tale of norepinephrine and drug addiction

D Weinshenker, JP Schroeder - Neuropsychopharmacology, 2007 - nature.com
Fueled by anatomical, electrophysiological, and pharmacological analyses of endogenous
brain reward systems, norepinephrine (NE) was identified as a key mediator of both natural …

Organization of the human inferior parietal lobule based on receptor architectonics

S Caspers, A Schleicher, M Bacha-Trams… - Cerebral …, 2013 - academic.oup.com
Human inferior parietal lobule (IPL) plays a key role in various cognitive functions. Its
functional diversity, including attention, language, and action processing, is reflected by its …

Inhibition of glycogenolysis in astrocytes interrupts memory consolidation in young chickens

ME Gibbs, DG Anderson, L Hertz - Glia, 2006 - Wiley Online Library
Glycolysis and glycogenolysis are involved in memory processing in day‐old chickens and,
aside from the provision of energy for neuronal and astrocytic energy metabolism these …

Compensatory changes in the noradrenergic nervous system in the locus ceruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia …

P Szot, SS White, JL Greenup, JB Leverenz… - Journal of …, 2006 - Soc Neuroscience
In Alzheimer's disease (AD), there is a significant loss of locus ceruleus (LC) noradrenergic
neurons. However, functional and anatomical evidence indicates that the remaining …

Cellular receptors of amyloid β oligomers (AβOs) in Alzheimer's disease

B Mroczko, M Groblewska, A Litman-Zawadzka… - International journal of …, 2018 - mdpi.com
It is estimated that Alzheimer's disease (AD) affects tens of millions of people, comprising not
only suffering patients, but also their relatives and caregivers. AD is one of age-related …

The role of lactate-mediated metabolic coupling between astrocytes and neurons in long-term memory formation

MQ Steinman, V Gao, CM Alberini - Frontiers in integrative …, 2016 - frontiersin.org
Long-term memory formation, the ability to retain information over time about an experience,
is a complex function that affects multiple behaviors, and is an integral part of an individual's …