In radiotherapy, radiation-quality should be an expression of the biological and physical
characteristics of ionizing radiation such as spatial distribution of ionization or energy …

This review explores current experimental methods for determining the radiation quality in
ion beams. In this context, radiation quality is commonly evaluated using the averaged linear …

Background Clinical data suggest that the relative biological effectiveness (RBE) in proton
therapy (PT) varies with linear energy transfer (LET). However, LET calculations are neither …

Proton beams are widely used worldwide to treat localized tumours, the lower entrance dose
and no exit dose, thus sparing surrounding normal tissues, being the main advantage of this …

Background Proton arc technology has recently shown dosimetric gains for various
treatment indications. The increased number of beams and energy layers (ELs) in proton arc …

Purpose To integrate dose-averaged linear energy transfer (LETd) into spot-scanning proton
arc therapy (SPArc) optimization and to explore its feasibility and potential clinical benefits …

Background Both dose and linear energy transfer (LET) could play a substantial role in
adverse event (AE) initialization of cancer patients treated with pencil‐beam‐scanning …

We developed a highly-selective technique to measure the energy loss and linear-energy-
transfer (LET) spectra of energetic charged particles in high-resolution and over a large …

Objective. Protons have advantageous dose distributions and are increasingly used in
cancer therapy. At the depth of the Bragg peak range, protons produce a mixed radiation …

Purpose To present particle arc therapy treatments using single and multi‐ion therapy
optimization strategies with helium (4He), carbon (12C), oxygen (16O), and neon (20Ne) ion …