Mechanisms and therapy for cancer metastasis to the brain

F Franchino, R Rudà, R Soffietti - Frontiers in oncology, 2018 - frontiersin.org
Advances in chemotherapy and targeted therapies have improved survival in cancer
patients with an increase of the incidence of newly diagnosed brain metastases (BMs) …

[HTML][HTML] Management of oligometastatic non-small cell lung cancer patients: Current controversies and future directions

F Couñago, J Luna, LL Guerrero… - World Journal of …, 2019 - ncbi.nlm.nih.gov
Oligometastatic non-small cell lung cancer (NSCLC) describes an intermediate stage of
NSCLC between localized and widely-disseminated disease. This stage of NSCLC is …

Operative and peri‐operative considerations in the management of brain metastasis

EW Sankey, V Tsvankin, MM Grabowski… - Cancer …, 2019 - Wiley Online Library
The number of patients who develop metastatic brain lesions is increasing as the diagnosis
and treatment of systemic cancers continues to improve, resulting in longer patient survival …

[HTML][HTML] Outcomes of patients with brain metastases from renal cell carcinoma receiving first-line therapies: results from the International Metastatic Renal Cell …

K Takemura, A Lemelin, MS Ernst, JC Wells… - European Urology, 2024 - Elsevier
Patients with brain metastases (BrM) from renal cell carcinoma and their outcomes are not
well characterized owing to frequent exclusion of this population from clinical trials. We …

Identification of risk factors associated with leptomeningeal disease after resection of brain metastases

RA Morshed, S Saggi, DD Cummins… - Journal of …, 2023 - thejns.org
OBJECTIVE Resection of brain metastases (BMs) may be associated with increased risk of
leptomeningeal disease (LMD). This study examined rates and predictors of LMD, including …

Opportunities and alternatives of modern radiation oncology and surgery for the management of resectable brain metastases

CD Diehl, FA Giordano, AL Grosu, S Ille, KH Kahl… - Cancers, 2023 - mdpi.com
Simple Summary Brain metastases are of increasing concern in the management of cancer
patients. New systemic treatment options like specific targeting agents or immune …

Stereotactic radiosurgery for resected brain metastases: single-institutional experience of over 500 cavities

S Shi, N Sandhu, MC Jin, E Wang, J Abi Jaoude… - International Journal of …, 2020 - Elsevier
Purpose Postoperative stereotactic radiosurgery (SRS) has less detrimental effect on
cognition and quality of life compared with whole brain radiation therapy (WBRT) and is …

Canadian consensus: oligoprogressive, pseudoprogressive, and oligometastatic non-small-cell lung cancer

SA Laurie, S Banerji, N Blais, S Brule… - Current …, 2019 - pmc.ncbi.nlm.nih.gov
Background Little evidence has been generated for how best to manage patients with non-
small-cell lung cancer (nsclc) presenting with rarer clinical scenarios, including …

Current status and recent advances in resection cavity irradiation of brain metastases

G Minniti, M Niyazi, N Andratschke, M Guckenberger… - Radiation …, 2021 - Springer
Despite complete surgical resection brain metastases are at significant risk of local
recurrence without additional radiation therapy. Traditionally, the addition of postoperative …

Targeted opening of the blood-brain barrier using VCAM-1 functionalised microbubbles and “whole brain” ultrasound

VA Johanssen, JL Ruan, O Vince, A Thomas… - …, 2024 - pmc.ncbi.nlm.nih.gov
Metastatic tumours in the brain now represent one of the leading causes of death from
cancer. Current treatments are largely ineffective owing to the combination of late diagnosis …