Animal models of traumatic brain injury

Y Xiong, A Mahmood, M Chopp - Nature Reviews Neuroscience, 2013 - nature.com
Traumatic brain injury (TBI) is a leading cause of mortality and morbidity both in civilian life
and on the battlefield worldwide. Survivors of TBI frequently experience long-term disabling …

Traumatic brain injury: an overview of pathobiology with emphasis on military populations

I Cernak, LJ Noble-Haeusslein - Journal of Cerebral Blood …, 2010 - journals.sagepub.com
This review considers the pathobiology of non-impact blast-induced neurotrauma (BINT).
The pathobiology of traumatic brain injury (TBI) has been historically studied in experimental …

Cumulative head impact burden in high school football

SP Broglio, JT Eckner, D Martini, JJ Sosnoff… - Journal of …, 2011 - liebertpub.com
Impacts to the head are common in collision sports such as football. Emerging research has
begun to elucidate concussion tolerance levels, but sub-concussive impacts that do not …

Long-term upregulation of inflammation and suppression of cell proliferation in the brain of adult rats exposed to traumatic brain injury using the controlled cortical …

SA Acosta, N Tajiri, K Shinozuka, H Ishikawa… - PloS one, 2013 - journals.plos.org
The long-term consequences of traumatic brain injury (TBI), specifically the detrimental
effects of inflammation on the neurogenic niches, are not very well understood. In the …

Mapping the functional connectome in traumatic brain injury: What can graph metrics tell us?

K Caeyenberghs, H Verhelst, A Clemente, PH Wilson - Neuroimage, 2017 - Elsevier
Objective Traumatic brain injury (TBI) is associated with cognitive and motor deficits, and
poses a significant personal, societal, and economic burden. One mechanism by which TBI …

Resistance, vulnerability and resilience: a review of the cognitive cerebellum in aging and neurodegenerative diseases

KJ Liang, ES Carlson - Neurobiology of learning and memory, 2020 - Elsevier
In the context of neurodegeneration and aging, the cerebellum is an enigma. Genetic
markers of cellular aging in cerebellum accumulate more slowly than in the rest of the brain …

The young brain and concussion: imaging as a biomarker for diagnosis and prognosis

E Toledo, A Lebel, L Becerra, A Minster… - Neuroscience & …, 2012 - Elsevier
Concussion (mild traumatic brain injury (mTBI)) is a significant pediatric public health
concern. Despite increased awareness, a comprehensive understanding of the acute and …

Deranged calcium signaling in Purkinje cells and pathogenesis in spinocerebellar ataxia 2 (SCA2) and other ataxias

A Kasumu, I Bezprozvanny - The Cerebellum, 2012 - Springer
Spinocerebellar ataxias (SCAs) constitute a heterogeneous group of more than 30
autosomal-dominant genetic and neurodegenerative disorders. SCAs are generally …

Omega-3 polyunsaturated fatty acid supplementation improves neurologic recovery and attenuates white matter injury after experimental traumatic brain injury

H Pu, Y Guo, W Zhang, L Huang… - Journal of Cerebral …, 2013 - journals.sagepub.com
Dietary supplementation with omega-3 (ω-3) fatty acids is a safe, economical mean of
preventive medicine that has shown protection against several neurologic disorders. The …

Slip chip device and methods

RF Ismagilov, W Du, L Li, F Shen, KPF Nichols… - US Patent …, 2016 - Google Patents
A device is described having a first surface having a plurality of first areas and a second
surface having a plurality of second areas. The first surface and the second surface are …