Comorbidity is associated with worse health outcomes, more complex clinical management,
and increased health care costs. There is no agreement, however, on the meaning of the …

Background and purpose The caregiving's impact on informal carers' quality of life and
gender-based stereotypes make older individuals' informal care a complex process for …

Advances in bacterial deoxyribonucleic acid sequencing allow for characterization of the
human commensal bacterial community (microbiota) and its corresponding genome …

Background. Hospitalization represents a stressful and potentially hazardous event for older
persons. We evaluated the value of the Short Physical Performance Battery (SPPB) in …

OBJECTIVES: To update previous guidelines to score the Cumulative Illness Rating Scale
(CIRS) and test their usefulness in hospitalized elderly patients. DESIGN: The CIRS was …

Purpose. To present a systematic literature review on the state of the art of the utilisation of
the International Classification of Functioning, Disability and Health (ICF) since its release in …

Objective. We aimed to disentangle the effect of chronic multimorbidity and disability on 3‐
year functional decline and survival in the elderly. Design. Prospective cohort study with a …

The increased prevalence of type 2 diabetes mellitus (T2DM) and life expectancy of diabetic
patients fosters the worldwide prevalence of retinopathy and nephropathy, two major …

Introduction The proportion of the elderly is constantly increasing and by the year 2025 20%
of the population will be above 65 years of age. With advanced age, subjects will develop …

The path to improving healthcare quality for individuals with complex health conditions is
complicated by a lack of common understanding of complexity. Modern medicine, together …