The disorder now known as vitiligo was first described by Claude Nicolas Le Cat in 1765. 1
However, the first specific consideration of a genetic component in vitiligo did not come until …

Vitiligo is a common dermatological disorder characterized by the presence on the skin of
depigmented macules resulting from the destruction of cutaneous melanocytes …

Background Autoimmune and autoinflammatory diseases involve interactions between
genetic risk factors and environmental triggers. We searched for a gene on chromosome …

We conducted a genome-wide association study of generalized vitiligo in the Chinese Han
population by genotyping 1,117 cases and 1,429 controls. The 34 most promising SNPs …

Recent findings provide evidence of inflammasome critical role in the predisposition to
autoimmune disorders. The involvement of inflammasome in the pathogenesis of systemic …

Vitiligo is a complex disease in which autoimmune destruction of epidermal melanocytes
results in patches of depigmented white skin. Vitiligo has an estimated prevalence of about …

Generalized vitiligo (GV) is a complex disease in which patchy depigmentation results from
autoimmune loss of melanocytes from affected regions. Genetic analyses of GV span six …

Background Autoimmune mechanisms are thought to have a major role in the pathogenesis
of multiple sclerosis. We aimed to identify coexisting autoimmune phenotypes in patients …

Generalized vitiligo is an acquired disorder in which white patches of skin and overlying hair
result from autoimmune loss of melanocytes from involved areas. The autoimmune …

Genetic dissection of human systemic lupus erythematosus (SLE) has been under intense
studies during the past decade. Although the complexity inherent to polygenic, multifactorial …