CM Kloske, CJ Barnum, AF Batista… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION At the Alzheimer's Association's APOE and Immunity virtual conference, held in October 2021, leading neuroscience experts shared recent research advances on …
M Régy, A Dugravot, S Sabia, C Helmer… - The Lancet Healthy …, 2024 - thelancet.com
Background The ε4 allele of the apolipoprotein E gene (APOE4) plays a role in neurodegeneration and in cardiovascular disease, but findings on its association with …
J Weiss, S Hossain, AI Maldonado, B Shen… - Scientific reports, 2021 - nature.com
We examined associations between cognition and mortality and how these relationships vary by race and Apolipoprotein E (APOE) genotype, in a longitudinal study of 2346 middle …
Background Clinical trials in older adults are increasingly focused on functional outcomes, and the composite outcome of dementia, disability, and death is gaining pivotal importance …
BACKGROUND: APOE is a known genetic contributor to cardiovascular disease, but the differential role APOE alleles play in subclinical atherosclerosis remains unclear …
J Mares, AP Costa, WJ Dartora… - Frontiers in Aging …, 2024 - frontiersin.org
Introduction At least one-third of the identified risk alleles from Genome-Wide Association Studies (GWAS) of Alzheimer's disease (AD) are involved in lipid metabolism, lipid transport …
The term “Primary age-related tauopathy”(PART) was coined in 2014 to describe the common neuropathological observation of neurofibrillary tangles without associated beta …
C Lachner, GS Day, GB Camsari… - Journal of …, 2022 - content.iospress.com
Background: Dementia, vascular disease, and cancer increase with age, enabling complex comorbid interactions. Understanding vascular and cancer contributions to dementia risk …
HY Park, HM Oh, TW Kim, Y Kim, GY Park… - Current Issues in …, 2022 - mdpi.com
This study aimed to evaluate whether genetic polymorphism is associated with an increased risk of infection, specifically post-stroke aspiration pneumonia. Blood samples were obtained …