Amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis is a fatal CNS neurodegenerative disease. Despite intensive
research, current management of amyotrophic lateral sclerosis remains suboptimal from …
research, current management of amyotrophic lateral sclerosis remains suboptimal from …
Current state and future directions in the therapy of ALS
L Tzeplaeff, S Wilfling, MV Requardt, M Herdick - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder
affecting upper and lower motor neurons, with death resulting mainly from respiratory failure …
affecting upper and lower motor neurons, with death resulting mainly from respiratory failure …
Pharmacotherapy for amyotrophic lateral sclerosis: a review of approved and upcoming agents
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder
involving loss of upper and lower motor neurons, with most cases ending in death within 3–5 …
involving loss of upper and lower motor neurons, with most cases ending in death within 3–5 …
Searching for peripheral biomarkers in neurodegenerative diseases: the tryptophan-kynurenine metabolic pathway
Neurodegenerative diseases are multifactorial, initiated by a series of the causative complex
which develops into a certain clinical picture. The pathogenesis and disease course vary …
which develops into a certain clinical picture. The pathogenesis and disease course vary …
Exploring the etiological links behind neurodegenerative diseases: Inflammatory cytokines and bioactive kynurenines
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common
neurodegenerative diseases (NDs), presenting a broad range of symptoms from motor …
neurodegenerative diseases (NDs), presenting a broad range of symptoms from motor …
Motor neuron susceptibility in ALS/FTD
AMG Ragagnin, S Shadfar, M Vidal… - Frontiers in …, 2019 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the
death of both upper and lower motor neurons (MNs) in the brain, brainstem and spinal cord …
death of both upper and lower motor neurons (MNs) in the brain, brainstem and spinal cord …
Genetics of amyotrophic lateral sclerosis
Abstract Purpose of Review Amyotrophic lateral sclerosis and frontotemporal dementia (ALS-
FTD) spectrum disorder is a rare fatal disease with strong genetic influences. The …
FTD) spectrum disorder is a rare fatal disease with strong genetic influences. The …
Sensory neuropathy in amyotrophic lateral sclerosis: a systematic review
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the degeneration of both upper and lower motoneurons, leading to motor and non-motor …
the degeneration of both upper and lower motoneurons, leading to motor and non-motor …
Non-motor symptoms in amyotrophic lateral sclerosis: lessons from Parkinson's disease
A Shojaie, S Rota, A Al Khleifat… - … Lateral Sclerosis and …, 2023 - Taylor & Francis
Amyotrophic lateral sclerosis and Parkinson's disease are neurodegenerative diseases of
the motor system which are now recognized also to affect non-motor pathways. Non-motor …
the motor system which are now recognized also to affect non-motor pathways. Non-motor …
A systematic review of non-motor symptom evaluation in clinical trials for amyotrophic lateral sclerosis
Background Amyotrophic lateral sclerosis (ALS) is increasingly recognised as a multi-
system disorder, presenting with common and impactful non-motor symptoms, such as …
system disorder, presenting with common and impactful non-motor symptoms, such as …