Combined microfluidics and drying processes for the continuous production of micro-/nanoparticles for drug delivery: a review

A Patil, P Patil, S Pardeshi, P Shrimal, N Rebello… - Drying …, 2023 - Taylor & Francis
Drug nanonization and encapsulation efficiency enhancement are prerequisites for
hydrophobic and hydrophilic drugs to be delivered at the targeted site. Microfluidic …

Process optimization for spray dried Aegle marmelos fruit nanomucilage: Characterization, functional properties, and in vitro antibiofilm activity against food …

M Sharma, A Bains, K Sridhar, P Chawla… - International Journal of …, 2023 - Elsevier
Recently, mucilage extraction from plant sources has been remarkably explored due to its
potential applications. Several underutilized fruits such as Aegle marmelos are the potential …

A critical review on developments in drying technologies for enhanced stability and bioavailability of pharmaceuticals

K Jadhav, E Kole, R Singh, SK Rout, RK Verma… - Drying …, 2024 - Taylor & Francis
Drying is a widely adopted unit operation that enhances the stability of pharmaceuticals.
Conventionally, freeze-drying has been chosen, as evidenced by the numerous freeze-dried …

Radio frequency-assisted ultrasonic spray freeze drying for pharmaceutical protein solids

TT Mutukuri, A Darwish, AD Strongrich… - Journal of …, 2023 - Elsevier
This study examined physical stability of spray freeze dried (SFD) bovine serum albumin
(BSA) solids produced using the radio frequency (RF)-assisted drying technique. BSA …

Tailoring dry microparticles for pulmonary drug delivery: ultrasonic spray freeze-drying with mannitol and salbutamol sulphate

L Pasero, F Susa, R Chiavarino, T Limongi, A Sulpizi… - Processes, 2023 - mdpi.com
Spray freeze-drying has emerged as a valid alternative to traditional spray drying to produce
therapeutic dry microparticles. In particular, the spherical shape and high porosity of spray …

Industrial-scale experimental study of internal-mixing air-blast nozzle for sludge atomization

C Yu, Y Cui, B Liu, Y Li, R Wang, C He, J Li… - Drying …, 2023 - Taylor & Francis
The atomization of sewage sludge is a key step in its drying process. This study conducts an
industrial-scale experimental study to investigate the performance of a self-developed …

[HTML][HTML] A diffused-interface model for the lyophilization of a packed bed of spray-frozen particles

L Stratta, MB Adali, AA Barresi, G Boccardo… - Chemical Engineering …, 2023 - Elsevier
Spray freeze-drying is particularly suitable for the preservation of biopharmaceuticals as it
involves gentle drying and can easily be integrated with continuous manufacturing …

Dandelion inspired microparticles with highly efficient drug delivery to deep lung

H Sun, S Yan, C Wu, J Ma, K Lu, X Cheng… - Colloids and Surfaces B …, 2024 - Elsevier
Active pharmaceutical ingredient (API) embedded dry powder for inhalation (AeDPI) shows
higher drug loading and delivery dose for directly treating various lung infections. Inspired …

[HTML][HTML] In-vial printing and drying of biologics as a personalizable approach

D Fiedler, C Alva, JT Pinto, M Spoerk, R Jeitler… - International Journal of …, 2022 - Elsevier
This study addressed the need for a flexible (personalizable) production of biologics,
allowing their stabilization in the solid state and processing of small batch volumes …

Spray freezing: An overview of applications and modeling

M Mohit, M Xu, JC Kurnia, AS Mujumdar… - Drying …, 2024 - Taylor & Francis
Spray freezing technology finds broad applications across various industries such as food
and pharmaceutical, mining, and water treatment. The significance of spray freezing is to …