An appropriate balance between self-renewal and differentiation is crucial for stem cell
function during both early development and tissue homeostasis throughout life. Recent …

Mesenchymal stromal cells (MSCs) are promising candidates for tissue engineering and
regenerative medicine. The multipotent stem cell component of MSC isolates is able to …

Background Bone marrow-derived mesenchymal stem cell (BMSC) transplantation is one of
the new therapeutic strategies for treating ischemic brain and heart tissues. However, the …

Reactive oxygen species (ROS) have long been considered as pathological agents
inducing apoptosis under adverse culture conditions. However, recent findings have …

The generation of reactive oxygen species (ROS) and an imbalance of antioxidant defence
mechanisms can result in oxidative stress. Several pro-atherogenic stimuli that promote …

Cardiovascular diseases are major causes of mortality and morbidity. Cardiomyocyte
apoptosis disrupts cardiac function and leads to cardiac decompensation and terminal heart …

Introduction Bone marrow mesenchymal stem cells/multipotent stromal cells (MSCs) are
recruited to sites of injury and subsequently support regeneration through differentiation or …

Autophagy is a dynamic process that maintains the normal homeostasis of cells by digesting
and degrading aging proteins and damaged organelles. The effect of autophagy on neural …

Under a variety of physical and experimental settings, stem cells are able to self-renew and
differentiate into specialized adult cells. MSCs (mesenchymal stromal/stem cells) are …

Background Transplantation of mesenchymal stem cells (MSC) has been proposed to
improve wound healing. However, as these cells only transiently survive in the implantation …