Emerging evidence indicates that moderate intensity aerobic exercise is positively
correlated with cognitive function and memory. However, the exact mechanisms underlying …

Altered neurogenesis is suggested to be involved in the onset of brain diseases, including
mental disorders and neurodegenerative diseases. Neurotrophic factors are well known for …

The function of the brain-derived neurotrophic factor (BDNF) via activation through its high-
affinity receptor Tropomyosin receptor kinase B (TrkB) has a pivotal role in cell …

With the increasing prevalence of Alzheimer's disease (AD) and difficulties in finding
effective treatments, it is essential to discover alternative therapies through new approaches …

Aim Acrylamide (ACR) is an environmental pollutant with well-demonstrated neurotoxic and
neurodegenerative effects in both humans and experimental animals. The present study …

Abstract Alzheimer's disease (AD), which is characterized by extracellular accumulation of
amyloid-beta peptide and intracellular aggregation of hyperphosphorylated tau, is the most …

A growing body of evidence demonstrates the important role of the noradrenergic system in
the pathogenesis of many neurodegenerative processes, especially Alzheimer's disease …

Accumulating evidence suggest that aberrations of neurotrophic factors are involved in the
etiology and pathogenesis of Alzheimer's disease (AD), but clinical data were inconsistent …

Background Alzheimer's disease (AD) is one of the major threats of the twenty-first century
and lacks available therapy. Identification of novel molecular markers for diagnosis and …

Alzheimer's disease (AD) is a worldwide problem and there are no effective drugs for AD
treatment. Previous studies show that DL0410 is a multi-target, anti-AD agent. In this study …