Transition-metal catalyzed reactions that are able to construct complex aliphatic amines from
simple, readily available feedstocks have become a cornerstone of modern synthetic …

Catalytic transformation of ubiquitous C–H bonds into valuable C–N bonds offers an efficient
synthetic approach to construct N-functionalized molecules. Over the last few decades …

Although carbon is the central element of organic chemistry, oxygen is the central element of
stereoelectronic control in organic chemistry. Generally, a molecule with a C–O bond has …

C–H bonds are ubiquitous structural units of organic molecules. Although these bonds are
generally considered to be chemically inert, the recent emergence of methods for C–H …

Abstract α-Amino acids are essential for life as building blocks of proteins and components
of diverse natural molecules. In both industry and academia, the incorporation of unnatural …

Reactions that directly install nitrogen into C–H bonds of complex molecules are significant
because of their potential to change the chemical and biological properties of a given …

In chemistry, a nucleophile is a molecule or ion with a lone pair of electrons. It donates both
bonding electrons to its reaction partner (the electrophile) when forming a chemical bond. 1 …

C H oxidation has a long history and an ongoing presence in research at the forefront of
chemistry and interrelated fields. As such, numerous highly useful articles and reviews have …

A catalytic system for intermolecular benzylic C (sp3)–H amination is developed utilizing 1,
2, 3, 4-tetrazole as a nitrene precursor via iron catalysis. This method enables direct …

Effective differentiation of prochiral carbon–hydrogen (C–H) bonds on a single methylene
carbon via asymmetric metal insertion remains a challenge. Here, we report the discovery of …