Cellular stresses and stress responses in the pathogenesis of insulin resistance

AN Onyango - Oxidative medicine and cellular longevity, 2018 - Wiley Online Library
Insulin resistance (IR), a key component of the metabolic syndrome, precedes the
development of diabetes, cardiovascular disease, and Alzheimer's disease. Its etiological …

Fructose-mediated effects on gene expression and epigenetic mechanisms associated with NAFLD pathogenesis

JK DiStefano - Cellular and Molecular Life Sciences, 2020 - Springer
Nonalcoholic fatty liver disease (NAFLD) is a chronic, frequently progressive condition that
develops in response to excessive hepatocyte fat accumulation (ie, steatosis) in the absence …

[HTML][HTML] Changes in pancreatic histology, insulin secretion and oxidative status in diabetic rats following treatment with Ficus deltoidea and vitexin

S Nurdiana, YM Goh, H Ahmad, SM Dom… - … and alternative medicine, 2017 - Springer
Background The potential application of Ficus deltoidea and vitexin for the management of
symptomatologies associated with diabetes mellitus (DM) has gained much attention …

Metabolic syndrome as a multifaceted risk factor for oxidative stress

S Spahis, JM Borys, E Levy - Antioxidants & redox signaling, 2017 - liebertpub.com
Abstract Significance: Metabolic syndrome (MetS) is associated with a greater risk of
diabetes and cardiovascular diseases. It is estimated that this multifactorial condition affects …

Doxorubicin caused severe hyperglycaemia and insulin resistance, mediated by inhibition in AMPk signalling in skeletal muscle

EA de Lima Junior, AS Yamashita… - Journal of cachexia …, 2016 - Wiley Online Library
Background Cancer is considered the second leading cause of death in the world, and for
the treatment of this disease, pharmacological intervention strategies are frequently based …

[HTML][HTML] Dihydro-Resveratrol attenuates oxidative stress, adipogenesis and Insulin Resistance in in Vitro models and High-Fat Diet-Induced Mouse Model via AMPK …

CS Lam, YX Xia, BS Chen, YX Du, KL Liu, HJ Zhang - Nutrients, 2023 - mdpi.com
Management of obesity has become a prevalent strategy for preventing the diseases closely
integrated with excess body weight such as diabetes over the last half century. Searching for …

[HTML][HTML] High fructose intake and adipogenesis

A Hernández-Díazcouder, R Romero-Nava… - International journal of …, 2019 - mdpi.com
In modern societies, high fructose intake from sugar-sweetened beverages has contributed
to obesity development. In the diet, sucrose and high fructose corn syrup are the main …

Dietary advanced glycation end products shift the gut microbiota composition and induce insulin resistance in mice

J Wang, W Cai, J Yu, H Liu, S He, L Zhu… - … Syndrome and Obesity …, 2022 - Taylor & Francis
Objective This study aimed to explore the associations between gut microbiota
characteristics and glycometabolic profiles in mice fed diets high in advanced glycation end …

[HTML][HTML] Fructose promotes angiogenesis by improving vascular endothelial cell function and upregulating VEGF expression in cancer cells

Y Cui, H Liu, Z Wang, H Zhang, J Tian, Z Wang… - Journal of Experimental …, 2023 - Springer
Background Fructose is a very common sugar found in natural foods, while current studies
demonstrate that high fructose intake is significantly associated with increased risk of …

[HTML][HTML] The use of probiotic L. fermentum ME-3 containing Reg'Activ Cholesterol supplement for 4 weeks has a positive influence on blood lipoprotein profiles and …

T Kullisaar, K Zilmer, T Salum, A Rehema, M Zilmer - Nutrition journal, 2016 - Springer
Background Cardiovascular diseases continue to be a challenge and burden to heath. The
incidence of type 2 diabetes is increasing. Modifying the (common) risk factors of them is the …