Indanone-containing scaffolds are attractive synthetic targets because of their wide
occurrence in many natural products, drugs and functional materials. In the last few years …

New direct access to conjugated tetraenes has been achieved. A Ru (0)-catalysed reaction
of 1, 3-enynes with 1, 3-dienes gives 1, 3, 5, 7-octatetraene derivatives by formal …

Terminal allylic alcohols are important motifs in natural products, and also key intermediates/
precursors in numerous novel reaction transformations. In this study, enabled by a …

A one-pot step-economic tandem process involving (5+ 2)-cycloaddition and Nazarov
cyclization reactions has been reported for the facile synthesis of indanone-fused benzo [cd] …

Dienones are challenging building blocks in natural product synthesis due to their high
reactivity and complex synthesis. Based on previous work and own initial results, a new …

A range of alkene difunctionalization reactions have been developed by exploiting the aza-
Prilezhaev aziridination platform that uses hydroxylamine-derived NO donors. Under acidic …

In der vorliegenden Arbeit wird über Untersuchungen zu einem synthetischen Zugang zum
bakteriellen Sekundärmetaboliten Collinolacton berichtet. Der Naturstoff weist ein …

Pharmacophore design to inhibit the interaction between p53 and MDM2 became a novel
approach for cancer therapy. p53, known as the guardian of genome, controls the cell cycle …