Objective and methods This study reviewed the concept of in silico prediction of chemical
toxicity for prevention of occupational cancer and future prospects in workers' health. In this …

The exercise of non-testing approaches in nanoparticles (NPs) hazard assessment is
necessary for the risk assessment, considering cost and time efficiency, to identify, assess …

The widespread accumulation of nanoplastics is a growing concern for the environmental
and human health. However, studies on the mechanisms of nanoplastic-induced …

Sliver nanoparticles (AgNPs) are widely used in industry, agriculture, and medicine,
potentially resulting in adverse effects on human health and aquatic environments. Here, we …

The European market for pesticides is currently legislated through the well-developed
Regulation (EC) No. 1107/2009. This regulation promotes the competitiveness of European …

The heterogeneity of engineered nanomaterials (NMs), with respect to physicochemical
properties and observed (eco) toxicological effects, makes their case-by-case testing for …

The EU REACH legislation, the OECD and US EPA official guidance documents, as well as
the 3Rs principle (replacement, reduction, refinement of animal testing), all advocate the …

Over the past decade, computational nanotoxicology, in particular Quantitative Structure–
Activity Relationship models (Nano-QSAR) that help in assessing the biological effects of …

To keep pace with its rapid development an efficient approach for the risk assessment of
nanomaterials is needed. Grouping concepts as developed for chemicals are now being …

Neurodegenerative diseases involve progressive neuronal death. Traditional treatments
often struggle due to solubility, bioavailability, and crossing the Blood-Brain Barrier (BBB) …