Recent advances in in silico target fishing
In silico target fishing, whose aim is to identify possible protein targets for a query molecule,
is an emerging approach used in drug discovery due its wide variety of applications. This …
is an emerging approach used in drug discovery due its wide variety of applications. This …
Bioactive compound identification and in vitro evaluation of antidiabetic and cytotoxic potential of Garcinia atroviridis fruit extract
With a continuous threat of type 2 diabetes mellitus (T2DM) worldwide, efforts to discover
new alternatives are ongoing for its management. Therefore, the use of natural herbal …
new alternatives are ongoing for its management. Therefore, the use of natural herbal …
Pharmacological inhibition of endogenous hydrogen sulfide attenuates breast cancer progression
Hydrogen sulfide (H2S), a gaseous signaling molecule, is associated with the development
of various malignancies via modulating various cellular signaling cascades. Published …
of various malignancies via modulating various cellular signaling cascades. Published …
Anti-breast cancer synthetic peptides derived from the Anabastestudineus skin mucus fractions
Previous study has shown the antimicrobial activities of mucus protein extracted from
Anabas testudineus. In this study, we are interested in characterizing the anticancer activity …
Anabas testudineus. In this study, we are interested in characterizing the anticancer activity …
Marantodes pumilum: Systematic computational approach to identify their therapeutic potential and effectiveness
Ethnopharmacological relevance Marantodes pumilum (MP) herbs, locally known as Kacip
Fatimah, are widely used traditionally to improve women's health. The herb is frequently …
Fatimah, are widely used traditionally to improve women's health. The herb is frequently …
Antidiabetic potential of ethanolic crude extract of Garcinia atroviridis fruits: in vitro, in ovo, and in silico analysis
Various parts of Garcinia atroviridis have long been used to address various health issues
and as a seasoning. Past research has highlighted the leaf extracts' diverse medicinal …
and as a seasoning. Past research has highlighted the leaf extracts' diverse medicinal …
Screening of high-risk deleterious missense variations in the CYP1B1 gene implicated in the pathogenesis of primary congenital glaucoma: A comprehensive in silico …
Background Primary congenital glaucoma (PCG) is the most common subtype of glaucoma
caused by defects in the cytochrome P450 1B1 (CYP1B1) gene. It is developing among …
caused by defects in the cytochrome P450 1B1 (CYP1B1) gene. It is developing among …
In silico identification and in vitro assessment of a potential anti-breast cancer activity of antimicrobial peptide retrieved from the ATMP1 Anabas testudineus fish …
A previous study has shown that synthetic antimicrobial peptides (AMPs) derived from
Anabas testudineus (ATMP1) could in-vitro inhibit the progression of breast cancer cell lines …
Anabas testudineus (ATMP1) could in-vitro inhibit the progression of breast cancer cell lines …
Computational evaluation of bioactive compounds in Curcuma zanthorrhiza targeting SIRT1 and NFκB
Type 2 diabetes mellitus (T2DM) is the predominant form of diabetes worldwide and has
been rapidly increasing in recent years. Currently, around 500 million people have diabetes …
been rapidly increasing in recent years. Currently, around 500 million people have diabetes …
DM-MOGA: a multi-objective optimization genetic algorithm for identifying disease modules of non-small cell lung cancer
J Shang, X Zhu, Y Sun, F Li, X Kong, JX Liu - BMC bioinformatics, 2023 - Springer
Background Constructing molecular interaction networks from microarray data and then
identifying disease module biomarkers can provide insight into the underlying pathogenic …
identifying disease module biomarkers can provide insight into the underlying pathogenic …