Pathogenicity and virulence of Staphylococcus aureus

GYC Cheung, JS Bae, M Otto - Virulence, 2021 - Taylor & Francis
Staphylococcus aureus is one of the most frequent worldwide causes of morbidity and
mortality due to an infectious agent. This pathogen can cause a wide variety of diseases …

Staphylococcus aureus Toxins: An Update on Their Pathogenic Properties and Potential Treatments

N Ahmad-Mansour, P Loubet, C Pouget… - Toxins, 2021 - mdpi.com
Staphylococcus aureus is a clinically important pathogen that causes a wide range of
human infections, from minor skin infections to severe tissue infection and sepsis. S. aureus …

Staphylococcus aureus Secreted Toxins and Extracellular Enzymes

K Tam, VJ Torres - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a formidable pathogen capable of causing infections in different
sites of the body in a variety of vertebrate animals, including humans and livestock. A major …

[HTML][HTML] Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury

E Lefrançais, B Mallavia, H Zhuo, CS Calfee… - JCI insight, 2018 - ncbi.nlm.nih.gov
Neutrophils dominate the early immune response in pathogen-induced acute lung injury, but
efforts to harness their responses have not led to therapeutic advancements. Neutrophil …

Exploring the Role of Staphylococcus aureus in Inflammatory Diseases

H Chen, J Zhang, Y He, Z Lv, Z Liang, J Chen, P Li… - Toxins, 2022 - mdpi.com
Staphylococcus aureus is a very common Gram-positive bacterium, and S. aureus infections
play an extremely important role in a variety of diseases. This paper describes the types of …

Staphylococcal manipulation of host immune responses

V Thammavongsa, HK Kim, D Missiakas… - Nature Reviews …, 2015 - nature.com
Staphylococcus aureus, a bacterial commensal of the human nares and skin, is a frequent
cause of soft tissue and bloodstream infections. A hallmark of staphylococcal infections is …

Staphylococcus aureus toxins

M Otto - Current opinion in microbiology, 2014 - Elsevier
Highlights•S. aureus produces a wide variety of toxins mostly aimed to evade elimination by
host defenses.•Many S. aureus toxins are encoded on mobile genetic elements, leading to a …

Development of a vaccine against Staphylococcus aureus invasive infections: Evidence based on human immunity, genetics and bacterial evasion mechanisms

LS Miller, VG Fowler Jr, SK Shukla… - FEMS microbiology …, 2020 - academic.oup.com
Invasive Staphylococcus aureus infections are a leading cause of morbidity and mortality in
both hospital and community settings, especially with the widespread emergence of virulent …

Staphylococcus δ-toxin induces allergic skin disease by activating mast cells

Y Nakamura, J Oscherwitz, KB Cease, SM Chan… - Nature, 2013 - nature.com
Atopic dermatitis is a chronic inflammatory skin disease that affects 15–30% of children and
approximately 5% of adults in industrialized countries. Although the pathogenesis of atopic …

Neutrophils and immunity: from bactericidal action to being conquered

TS Teng, A Ji, XY Ji, YZ Li - Journal of immunology research, 2017 - Wiley Online Library
The neutrophil is the major phagocyte and the final effector cell of the innate immunity, with a
primary role in the clearance of extracellular pathogens. Using the broad array of cytokines …