Osteocytes, former osteoblasts encapsulated by mineralized bone matrix, are far from being
passive and metabolically inactive bone cells. Instead, osteocytes are multifunctional and …

The bone remodelling cycle replaces old and damaged bone and is a highly regulated,
lifelong process essential for preserving bone integrity and maintaining mineral …

The bone is an essential organ for locomotion and protection of the body, as well as
hematopoiesis and mineral homeostasis. In order to exert these functions throughout life …

Bone remodeling is the continual process to renew the adult skeleton through the sequential
action of osteoblasts and osteoclasts. Nuclear factor RANK, an osteoclast receptor, and its …

The biology of haematopoietic stem cells (HSCs) has predominantly been studied under
transplantation conditions,. It has been particularly challenging to study dynamic HSC …

Stay up on the latest research and techniques in endodontics with Cohen's Pathways of the
Pulp, 12th Edition. Written by a team of internationally renowned experts and trusted for …

Corticosteroid associated osteonecrosis is bone death resulting from the use of chronic
glucocorticoids and most commonly affects the femoral head, although the bones such as …

Osteoclasts resorb the mineralized matrices formed by chondrocytes or osteoblasts. The
cytokine receptor activator of nuclear factor-κB ligand (RANKL) is essential for osteoclast …

Uncontrolled inflammation is a leading cause of many clinically relevant diseases. Current
therapeutic strategies focus mainly on immunosuppression rather than on the mechanisms …

Estrogen deficiency has been considered the seminal mechanism of osteoporosis in both
women and men, but epidemiological evidence in humans and recent mechanistic studies …