Mycosis fungoides and Sézary syndrome: an update

C Larocca, T Kupper - Hematology/Oncology Clinics, 2019 - hemonc.theclinics.com
Cutaneous T-cell lymphomas (CTCLs) encompass a heterogeneous collection of non-
Hodgkin lymphomas that arise from skin-tropic memory T lymphocytes. Among them …

Artificial intelligence applications in dermatology: where do we stand?

A Gomolin, E Netchiporouk, R Gniadecki… - Frontiers in …, 2020 - frontiersin.org
Artificial intelligence (AI) has become a progressively prevalent Research Topic in medicine
and is increasingly being applied to dermatology. There is a need to understand this …

Cobomarsen, an oligonucleotide inhibitor of miR‐155, co‐ordinately regulates multiple survival pathways to reduce cellular proliferation and survival in cutaneous T …

AG Seto, X Beatty, JM Lynch… - British journal of …, 2018 - Wiley Online Library
Summary miR‐155, a microRNA associated with poor prognosis in lymphoma and
leukaemia, has been implicated in the progression of mycosis fungoides (MF), the most …

Single-cell RNA sequencing reveals markers of disease progression in primary cutaneous T-cell lymphoma

K Rindler, C Jonak, N Alkon, FM Thaler, H Kurz… - Molecular cancer, 2021 - Springer
Background In early-stage mycosis fungoides (MF), the most common primary cutaneous T-
cell lymphoma, limited skin involvement with patches and plaques is associated with a …

Tumor-associated macrophages: therapeutic targets for skin cancer

T Fujimura, Y Kambayashi, Y Fujisawa, T Hidaka… - Frontiers in …, 2018 - frontiersin.org
Tumor-associated macrophages (TAMs) and regulatory T cells (Tregs) are significant
components of the microenvironment of solid tumors in the majority of cancers. TAMs …

High-throughput sequencing of the T cell receptor β gene identifies aggressive early-stage mycosis fungoides

A De Masson, JT O'Malley, CP Elco… - Science translational …, 2018 - science.org
Mycosis fungoides (MF), the most common cutaneous T cell lymphoma (CTCL) is a
malignancy of skin-tropic memory T cells. Most MF cases present as early stage (stage IA/B …

Diagnosis of early mycosis fungoides

T Miyagaki - Diagnostics, 2021 - mdpi.com
Mycosis fungoides (MF), the most common type of cutaneous T-cell lymphomas, generally
has a favorable clinical course. Early MF typically presents erythematous patches and/or …

Mogamulizumab: a new tool for management of cutaneous T-cell lymphoma

TA Ollila, I Sahin, AJ Olszewski - OncoTargets and therapy, 2019 - Taylor & Francis
Cutaneous T-cell lymphoma (CTCL) poses unique treatment challenges, given its range of
presentations and numerous systemic therapy options. These options often lack …

Gene expression analysis in Cutaneous T-Cell Lymphomas (CTCL) highlights disease heterogeneity and potential diagnostic and prognostic indicators

IV Litvinov, MT Tetzlaff, P Thibault, P Gangar… - …, 2017 - Taylor & Francis
ABSTRACT Cutaneous T-Cell Lymphomas (CTCL) are rare, but potentially devastating
malignancies, whose pathogenesis remains poorly elucidated. Unfortunately, currently it is …

High activation of STAT5A drives peripheral T-cell lymphoma and leukemia

B Maurer, H Nivarthi, B Wingelhofer… - …, 2019 - pmc.ncbi.nlm.nih.gov
Recurrent gain-of-function mutations in the transcription factors STAT5A and much more in
STAT5B were found in hematopoietic malignancies with the highest proportion in mature T …