Insulin is a polypeptide hormone mainly secreted by β cells in the islets of Langerhans of the
pancreas. The hormone potentially coordinates with glucagon to modulate blood glucose …

It is increasingly apparent that not only is a cure for the current worldwide diabetes epidemic
required, but also for its major complications, affecting both small and large blood vessels …

The prevalence of diabetes mellitus (DM) is increasing worldwide, a consequence of the
alarming rise in obesity and metabolic syndrome (MetS). Oxidative stress and inflammation …

Insulin has complex effects on cell growth, metabolism and differentiation, and these effects
are mediated by a cell-surface bound receptor and eventually a cascade of intracellular …

Diabetes mellitus contributes greatly to morbidity, mortality, and overall health care costs. In
major part, these outcomes derive from the high incidence of progressive kidney dysfunction …

Diabetes and its complications, Alzheimer's disease (AD), and Parkinson's disease (PD) are
increasing gradually, reflecting a global threat vis‐à‐vis expressing the essentiality of a …

The aldosterone-sensitive distal nephron (ASDN) includes the late distal convoluted tubule
2, the connecting tubule (CNT) and the collecting duct. The appropriate regulation of sodium …

Diabetic kidney disease (DKD) is a progressive proteinuric renal disorder in patients with
type 1 or type 2 diabetes mellitus. It is a common cause of end-stage kidney disease …

Aims Our study was designed to explore the function and mechanism of taxifolin on glucose
metabolism and water-salt metabolism in kidney with metabolic syndrome (MS) rats. Main …

Insulin resistance (IR) is one of the significant aberrations in polycystic ovarian syndrome
(PCOS), however is only observed in 70%–80% of obese PCOS and 20%–25% of lean …